Güncel Gönderiler: Moleküler Biyoloji ve Genetik-Makale Koleksiyonu
Toplam kayıt 75, listelenen: 61-75
-
Identification of intracellular pathways through which TGF-beta 1 upregulates URG-4/URGCP gene expression in hepatoma cells
(Pergamon-Elsevier Science Ltd,, 2016)Aims: Up-regulated gene 4 (URG-4/URGCP) was strongly expressed in Hepatitis B infected liver and correlated with HBxAG (Hepatitis B x Antigen) protein and found to promote hepatocellular cancer. Transforming growth factor ... -
SP1 and USF differentially regulate ADAMTS1 gene expression under normoxic and hypoxic conditions in hepatoma cells
(Elsevier Science Bv, 2016)ADAM metallopeptidase with thrombospondin type I motif, 1 (ADAMTS1) that has both antiangiogenic and aggrecanase activity was dysregulated in many pathophysiologic circumstances. However, there is limited information ... -
The role of hypoxia response element in TGF beta-induced carbonic anhydrase IX expression in Hep3B human hepatoma cells
(Inst Bioloska Istrazivanja Sinisa Stankovic, 2017)Carbonic anhydrase IX (CAIX) is a hypoxia-regulated gene. It is overexpressed in a variety of cancers, including hepatocellular cancer. Transforming growth factor beta(TGF beta) is considered to have an impact on cancer ... -
In vitro effects of some pesticides on glutathione-s transferase activity
(Parlar Scientific Publications, 2017)Human populations have been constantly exposed to pesticides due to their extensive use and presence in food and drinking water. Therefore, the aim of this study is to compare the inhibitory effect of three commonly used ... -
SP1 is a transcriptional regulator of URG-4/URGCP gene in hepatocytes
(Springer, 2016)URG-4/URGCP gene was implicated as an oncogene that contributes hepatocarcinogenesis regulated by Hepatitis-B-virus-encoded X antigen. However, the mechanism of transcriptional regulation of this gene remains largely ... -
The adsorption of methyl violet on activated carbon from aqueous solutions
(Parlar Scientific Publications, 2017)In this study, the activated carbon was prepared from the pomegranate shell by chemical activation, characterized using BET, FTIR-ATR, XRD, SEM and DTA/TG and investigated the adsorption properties. The adsorption process ... -
Genome of wild olive and the evolution of oil biosynthesis
(Natl Acad Sciences, 2017)Here we present the genome sequence and annotation of the wild olive tree (Olea europaea var. sylvestris), called oleaster, which is considered an ancestor of cultivated olive trees. More than 50,000 protein-coding genes ... -
Novel debittering process of green table olives: application of -glucosidase bound onto superparamagnetic nanoparticles
(Taylor & Francis Ltd, 2018)In this work, the olive -glucosidase (-glu) enzyme was immobilized onto superparamagnetic nanoparticles (SPMNs). Moreover, immobilized enzyme was also used for the debittering process for natural edible olives from Edremit, ... -
Prodrugs for nitroreductase based cancer therapy-1: metabolite profile, cell cytotoxicity and molecular modeling ınteractions of nitro benzamides with ssap-ntrb
(Bentham Science Publ Ltd, 2018)Background: Directed Enzyme Prodrug Therapy (DEPT) as an alternative method against conventional cancer treatments, in which the non-toxic prodrug is converted to highly cytotoxic derivative, has attracted an ample attentions ... -
Biological properties of pmma/nhap and pmma/3-apt-nhap nanocomposites
(Taylor & Francis As, 2018)In this study, nanocomposite-implant materials with the filler materials, which are nanohydroxyapatite (nHAp) and nHAp modified by [3-(2-aminoethilamino)propyl]trimethoxysilane, using poly(methylmethacrylate) as a matrix ... -
Hemocompatibility, cytotoxicity, and genotoxicity of poly(methylmethacrylate)/nanohydroxyapatite nanocomposites synthesized by melt blending method
(Taylor & Francis As, 2018)The aim of this study was to show the hemocompatibility, cytotoxicity, and genotoxicity of nanocomposites that were synthesized with different molecular weights of poly(methyl methacrylate) (PMMA) and different concentrations ... -
SP1-mediated downregulation of ADAMTS3 gene expression in osteosarcoma models
(Elsevier Science, 2018)ADAMTS3 is a member of procollagen N-proteinase subfamily of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) gene family. It has an important function in the procollagen maturation process. The ... -
Synthesis and characterization of poly(acrylic acid)/organo-modified nanohydroxyapatite nanocomposites: thermal, optical and biocompatibility properties
(De Gruyter, 2018)The aim of this study was to investigate the structural, thermal, optical and biocompatibility properties of poly(acrylic acid)(PAA)/organo-modified nanohydroxyapatite (OM-nHAp) nanocomposites synthesized by solvent ... -
Comparison of polyphenol oxidase activity in different parts of deep water pink shrimp (Parapenaeus longirostris) by using L-DOPA substrate in Marmara Sea during the fishing season
(2013)Melanosis derin su pembe karidesinin pazar kaybı için önemli bir problemdir. Bunun sorumlusu olan polifenol oksidaz (PPO) enzim aktivitesidir. PPO’nun özelliğini daha iyi anlamak ve oluşan aktiviteyi düşürme amacı için, ... -
The bioinformatic and expression analysis of PSMD4 gene
(2018)26S proteasome non-ATPase subunit 4 (PSMD4) that has a molecular weight of 41 kDa is included on chromosome 1 (1q21.3). PSMD4 protein is a subunit of the 19S regulatory region in the 26S proteasome. The proteasome breaks ...