Yayın tarihi için Moleküler Biyoloji ve Genetik-Makale Koleksiyonu listeleme
Toplam kayıt 75, listelenen: 1-20
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Comparison of polyphenol oxidase activity in different parts of deep water pink shrimp (Parapenaeus longirostris) by using L-DOPA substrate in Marmara Sea during the fishing season
(2013)Melanosis derin su pembe karidesinin pazar kaybı için önemli bir problemdir. Bunun sorumlusu olan polifenol oksidaz (PPO) enzim aktivitesidir. PPO’nun özelliğini daha iyi anlamak ve oluşan aktiviteyi düşürme amacı için, ... -
Synthesis, spectroscopic characterization, and antimicrobial activities of Ni(II) and Fe(II) complexes with N -(2-hydroxyethyl)-5-nitrosalicylaldimine
(Taylor & Francis Ltd, 2013)Metal complexes [Ni(HL1)(2)H2O] (1) and [Fe(HL1)(2)] (2), where HL1 is the tridentate Schiff base N-(2-hydroxyethyl)-5-nitrosalicylaldimine, were synthesized and characterized by spectroscopic methods. The crystal structures ... -
In silico and expression analysis of urg-4/urgcp gene in different cancer cells
(Nobel Science and Research Center, 2015)Upregulated gene 4 (URG-4/URGCP) located in chromosome 7 (7p13), was originally suggested as one of the HBxAg upregulated genes in hepatoma cells and implicated in tumorogenesis process in different cells. In this study ... -
Phenolic content, antioxidant activities and stimulatory roles of citrus fruits on some lactic acid bacteria
(Inst Bioloska Istrazivanja Sinisa Stankovic, 2015)In this study, phenolic compounds and antioxidant activities in citrus fruits and their peels were determined, and their stimulatory roles on some lactic acid bacteria were investigated. Phenolic compounds in citrus fruits ... -
Antiproliferative activity of Humulus lupulus extracts on human hepatoma (Hep3B), colon (HT-29) cancer cells and proteases, tyrosinase, beta-lactamase enzyme inhibition studies
(Taylor & Francis Ltd, 2016)The aims of this study were to examine the antiproliferation of Humulus lupulus extracts on human hepatoma carcinoma (Hep3B) and human colon carcinoma (HT-29) cell lines along with enzyme inhibitory effects of the crude ... -
In vivo effects of curcumin on the paraoxonase, carbonic anhydrase, glucose-6-phosphate dehydrogenase and beta-glucosidase enzyme activities in dextran sulphate sodium-induced ulcerative colitis mice
(Taylor & Francis Ltd, 2016)Increases in the risk of infections and malignancy due to immune suppressive therapies of inflammatory bowel diseases (IBDs) have led the researchers to focus on more nontoxic and acceptable natural products like curcumin. ... -
SP1 is a transcriptional regulator of URG-4/URGCP gene in hepatocytes
(Springer, 2016)URG-4/URGCP gene was implicated as an oncogene that contributes hepatocarcinogenesis regulated by Hepatitis-B-virus-encoded X antigen. However, the mechanism of transcriptional regulation of this gene remains largely ... -
SP1 and USF differentially regulate ADAMTS1 gene expression under normoxic and hypoxic conditions in hepatoma cells
(Elsevier Science Bv, 2016)ADAM metallopeptidase with thrombospondin type I motif, 1 (ADAMTS1) that has both antiangiogenic and aggrecanase activity was dysregulated in many pathophysiologic circumstances. However, there is limited information ... -
Identification of intracellular pathways through which TGF-beta 1 upregulates URG-4/URGCP gene expression in hepatoma cells
(Pergamon-Elsevier Science Ltd,, 2016)Aims: Up-regulated gene 4 (URG-4/URGCP) was strongly expressed in Hepatitis B infected liver and correlated with HBxAG (Hepatitis B x Antigen) protein and found to promote hepatocellular cancer. Transforming growth factor ... -
Synthesis, characterization, antibacterial, and antifungal activities of one-dimensional O-H center dot center dot center dot O hydrogen-bonded Cu(II) and Ni(II) complexes
(Taylor & Francis Inc, 2016)Two Schiff base complexes, [Cu(HL)(2)], 1 and [Ni(HL)(2)], 2 [H2L = 2-((E)-(2-hydroxyethylimino)methyl)-1-naptaphenol] have been synthesized and characterized by elemental analysis, H-1 NMR, C-13 NMR, IR spectroscopy, and ... -
The adsorption of methyl violet on activated carbon from aqueous solutions
(Parlar Scientific Publications, 2017)In this study, the activated carbon was prepared from the pomegranate shell by chemical activation, characterized using BET, FTIR-ATR, XRD, SEM and DTA/TG and investigated the adsorption properties. The adsorption process ... -
Genome of wild olive and the evolution of oil biosynthesis
(Natl Acad Sciences, 2017)Here we present the genome sequence and annotation of the wild olive tree (Olea europaea var. sylvestris), called oleaster, which is considered an ancestor of cultivated olive trees. More than 50,000 protein-coding genes ... -
In vitro effects of some pesticides on glutathione-s transferase activity
(Parlar Scientific Publications, 2017)Human populations have been constantly exposed to pesticides due to their extensive use and presence in food and drinking water. Therefore, the aim of this study is to compare the inhibitory effect of three commonly used ... -
The role of hypoxia response element in TGF beta-induced carbonic anhydrase IX expression in Hep3B human hepatoma cells
(Inst Bioloska Istrazivanja Sinisa Stankovic, 2017)Carbonic anhydrase IX (CAIX) is a hypoxia-regulated gene. It is overexpressed in a variety of cancers, including hepatocellular cancer. Transforming growth factor beta(TGF beta) is considered to have an impact on cancer ... -
The bioinformatic and expression analysis of PSMD4 gene
(2018)26S proteasome non-ATPase subunit 4 (PSMD4) that has a molecular weight of 41 kDa is included on chromosome 1 (1q21.3). PSMD4 protein is a subunit of the 19S regulatory region in the 26S proteasome. The proteasome breaks ... -
Synthesis and characterization of poly(acrylic acid)/organo-modified nanohydroxyapatite nanocomposites: thermal, optical and biocompatibility properties
(De Gruyter, 2018)The aim of this study was to investigate the structural, thermal, optical and biocompatibility properties of poly(acrylic acid)(PAA)/organo-modified nanohydroxyapatite (OM-nHAp) nanocomposites synthesized by solvent ... -
SP1-mediated downregulation of ADAMTS3 gene expression in osteosarcoma models
(Elsevier Science, 2018)ADAMTS3 is a member of procollagen N-proteinase subfamily of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) gene family. It has an important function in the procollagen maturation process. The ... -
Hemocompatibility, cytotoxicity, and genotoxicity of poly(methylmethacrylate)/nanohydroxyapatite nanocomposites synthesized by melt blending method
(Taylor & Francis As, 2018)The aim of this study was to show the hemocompatibility, cytotoxicity, and genotoxicity of nanocomposites that were synthesized with different molecular weights of poly(methyl methacrylate) (PMMA) and different concentrations ... -
Biological properties of pmma/nhap and pmma/3-apt-nhap nanocomposites
(Taylor & Francis As, 2018)In this study, nanocomposite-implant materials with the filler materials, which are nanohydroxyapatite (nHAp) and nHAp modified by [3-(2-aminoethilamino)propyl]trimethoxysilane, using poly(methylmethacrylate) as a matrix ... -
Prodrugs for nitroreductase based cancer therapy-1: metabolite profile, cell cytotoxicity and molecular modeling ınteractions of nitro benzamides with ssap-ntrb
(Bentham Science Publ Ltd, 2018)Background: Directed Enzyme Prodrug Therapy (DEPT) as an alternative method against conventional cancer treatments, in which the non-toxic prodrug is converted to highly cytotoxic derivative, has attracted an ample attentions ...
