Balıkesir Üniversitesi Kurumsal Akademik Arşivi
DSpace@Balıkesir, Balıkesir Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve yayınların etkisini artırmak için telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
The novel metabolic bridges extending from liver to the bone: The liver-bone axis
(Galenos Publ House, 2026) Kırık, Ali
To the editor,
We read with great interest the article by Ayyildiz
et al. (1). We believe this study is valuable in terms of
investigating the role of non-alcoholic fatty liver disease
(NAFLD) in osteoporosis clinical practice. However, we
have several suggestions to strengthen the study.
The effects of sternotomy and thoracotomy on respiratory muscle strength
(Hatay Mustafa Kemal Üniversitesi Tıp Fakültesi Dekanlığı, 2026) Öztekin, Özerk; Hepağuşlar, Hasan; Girgin, A. Pelin; Albayrak, Gökhan; Ulugün, İlknur; Özdemir, Nezih; Çımrın, A. Hikmet; Hazan, Eyüp; Elar, Zahide
Objective: The aim of this prospective clinical study was to investigate the effects of sternotomy and thoracotomy on respiratory muscle
strength (RMS).
Method: After obtaining ethics committee approval and written informed consent from patients, 60 patients who underwent open
heart surgery using sternotomy (Sternotomy Group [SG], n=30) or lung surgery using thoracotomy (Thoracotomy Group [TG], n=30) were
included. Pulmonary function test (PFT) and respiratory muscle strength (RMS) test were performed before and after surgery to compare
forced expiratory volume during the first second of the breath (FEV1), forced vital capacity (FVC), maximal inspiratory pressure (Pİmax),
maximal expiratory pressure (PEmax), and sniff nasal inspiratory pressure (SNIP) between groups.
Results: Preoperative FEV1, FVC, Pİmax, PEmax, and SNIP were similar between groups (p>0.05) and were found to be decreased
significantly in the postoperative period (p<0.001). Postoperative FVC was significantly lower in SG than TG (p=0.021). The rates of
decrease in FVC and Pİmax were significantly higher in SG than TG (48.71% vs. 34.95% for FVC; p=0.04 and 38.38% vs. %32.8 for Pİmax;
p=0.04).
Conclusion: It is concluded that pulmonary functions and respiratory muscle strength may decrease after sternotomy and thoracotomy
procedures. However; pulmonary function (FVC) and RMS (Pimax) were more adversely affected following sternotomy compared to
thoracotomy during the early postoperative period.
The effects of folic acid supplementation on novel biomarkers of the endothelial function in rats with experimental periodontitis
(Galenos Publ House, 2026) Olgun, Ebru; Kul, Oğuz; Ercan, Nuray; Atmaca, Hasan Tarık; Anteplioğlu, Tuğçe
Objective: The aim of this study is to investigate the effect of folic acid (FA) supplementation on endothelial damage caused by periodontitis. Materials and Methods: 48 rats were divided randomly into five groups: healthy control, sham control, lipopolysaccharide-induced periodontitis (LPS), lipopolysaccharide-induced periodontitis with low-dose FA (4 mg/kg) (LPS+4), and high-dose FA (12 mg/kg) (LPS+12) administered groups. Rats were euthanized after 15 days of the first lipopolysaccharide injection. Circulating progenitor cells taken from each rat's blood samples were counted using flow cytometry. ADMA, CD34+, and CD133+ expression in periodontal and cardiac tissues were labeled by using immunoperoxidase method. Results: There were no differences among the groups regarding ADMA expression in periodontal tissues. However, the LPS group exhibited the highest expression levels of CD34+ and CD133+, which were significantly elevated compared to those in the healthy group. Statistically significant differences in all biomarkers were observed among the groups in the cardiac tissue. Flow cytometry analysis results did not differ in ADMA expression level, but CD34+ and CD133+ expression levels were statistically significant between groups. Conclusion: The results of our study suggest that periodontitis induces an increase in the expression of endothelial biomarkers, while folic acid supplementation exerts a beneficial effect on periodontitis- associated endothelial dysfunction.
The effects of active video games on physical performance: Experimental study
(Türkiye Klinikleri Yayınevi, 2026) Gürcan, Enes; Pündük, Zekine; Çelik, Ertuğrul
We designed this study to investigate whether
active video games affect physical characteristics in sedentary adults.
Material and Methods: Nineteen healthy adults aged 40-60 years were
included in the study. The participants classified as sedentary according to the International Physical Activity Questionnaire. Participants
were divided into 3 groups: “active video games” (n=7), “walking”
(n=6), and “control” (n=6). All participants underwent stork balance,
maximum muscle strength were applied before the intervention and
after 4 weeks of training. Results: There were no significant differences between groups in age, height, body weight, and body mass index
before the intervention. After the intervention, a significant decrease in
body weight and body mass index was observed in the active video
game group (p≤0.04). Regarding the muscle strength, maximum flexion and extension strength values increased significantly in both legs in
the walking group (flexion: p≤0.001, p≤0.01; extension: p≤0.05,
p≤0.02), while in the active video game group, significant increases in
flexion and extension strength were observed in the left leg (flexion:
p≤0.001, extension: p≤0.03). The muscle endurance, a slight increase
was observed on the right side in the active video game group (p≤0.05).
Balance time improved significantly only in the walking group, particularly in the left leg (p≤0.05). Conclusion: Active video games may be
a possible option for increasing physical activity, particularly in sedentary adults, compared to traditional walking.
The effect of workplace loneliness on burnout: The moderating role of extraversion personality trait
(Zonguldak Bülent Ecevit Üniversitesi, 2026) Ayyıldız, Umut
Workplace loneliness has garnered increasing attention from both researchers and practitioners recently due to its widespread prevalence and significant negative consequences. The rapid changes in work arrangements following the COVID-19 pandemic have further intensified this interest. However, compared to studies on loneliness in general life, research on workplace loneliness remains limited. Unlike previous studies, this research examines extraversion, a personality trait, as a moderating variable and investigates whether this personality trait impacts the relationship between workplace loneliness and burnout. Based on data collected from 467 employees across Türkiye, the study found that workplace loneliness positively affects burnout; extraversion moderates this effect; and as employees’ extraversion increases, the impact of workplace loneliness on their burnout decreases. In other words, extraverted employees experience less burnout than introverted employees when experiencing loneliness in the workplace. This finding is consistent with research conducted in Canada but contrasts with a study conducted in China. Considering the individualism/collectivism cultural characteristics of the societies in China, Türkiye, and Canada, this study suggests that the moderating factor is not solely extraversion or introversion, but rather whether the personality trait in question is one that is accepted by the society to which the individual belongs.
