| dc.contributor.author | Yılmaz, Begümhan | |
| dc.contributor.author | Doğan, Serap | |
| dc.contributor.author | Kasımoğulları, Serap Çelikler | |
| dc.date.accessioned | 2019-08-06T06:37:48Z | |
| dc.date.available | 2019-08-06T06:37:48Z | |
| dc.date.issued | 2018 | en_US |
| dc.identifier.issn | 0091-4037 | |
| dc.identifier.issn | 1563-535X | |
| dc.identifier.uri | https://doi.org/10.1080/00914037.2017.1331349 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12462/5845 | |
| dc.description | Yılmaz, Begümhan (Balikesir Author) | en_US |
| dc.description.abstract | The aim of this study was to show the hemocompatibility, cytotoxicity, and genotoxicity of nanocomposites that were synthesized with different molecular weights of poly(methyl methacrylate) (PMMA) and different concentrations of nanohydroxyapatite (nHAp). Different techniques to characterize the nanocomposites were used. The cytotoxicity and genotoxic effects of the polymers and nanocomposites on human lymphocytes were determined by acid phosphatase assay, viability test, and comet assay. Moreover, hemocompatibility test was performed. It was found that all of the PMMA/nHAp nanocomposites are highly hemocompatible and biocompatible, none of the nanocomposites showed a cytotoxic effect, and nHAp addition decreased the genotoxicity. | en_US |
| dc.description.sponsorship | Scientific Research Projects Commission of Balikesir University BAP 15/120
Scientific and Technological Research Council of Turkey (TUBITAK) | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | Taylor & Francis As | en_US |
| dc.relation.isversionof | 10.1080/00914037.2017.1331349 | en_US |
| dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
| dc.subject | Cytotoxicity | en_US |
| dc.subject | Genotoxicity | en_US |
| dc.subject | Hemocompatibility | en_US |
| dc.subject | Nanocomposite | en_US |
| dc.subject | Nanohydroxyapatite | en_US |
| dc.subject | PMMA | en_US |
| dc.title | Hemocompatibility, cytotoxicity, and genotoxicity of poly(methylmethacrylate)/nanohydroxyapatite nanocomposites synthesized by melt blending method | en_US |
| dc.type | article | en_US |
| dc.relation.journal | International Journal of Polymeric Materials and Polymeric Biomaterials | en_US |
| dc.contributor.department | Fen Edebiyat Fakültesi | en_US |
| dc.contributor.authorID | 0000-0002-8446-1116 | en_US |
| dc.identifier.volume | 67 | en_US |
| dc.identifier.issue | 6 | en_US |
| dc.identifier.startpage | 351 | en_US |
| dc.identifier.endpage | 360 | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
