Güncel Gönderiler: Temel Tıp Bilimleri
Toplam kayıt 319, listelenen: 81-100
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Sıtma modelinde cinnamaldehyde, cannabidiol ve eravacycline’in etkinliğinin araştırılması
(2023)Bu çalışmada, güçlü antimikrobiyal etkinliği gibi çeşitli biyolojik aktiviteleri gösterilmiş olan ‘cinnamaldehyde’ (CIN) ve ‘cannabidiol’ (CBD) ile yeni nesil tetrasiklin türevi olan ‘eravacycline’ (ERA)’in antimalaryal ... -
Gentamisine Bağlı Nefrotoksisiteyi Önleme Potansiyeli Olan Tedavilerin Gözden Geçirilmesi
(2023)Aminoglikozitler, düşük maliyetleri, yüksek etkililikleri ve diğer antibiyotiklere kıyasla nispeten düşük bakteri direncine sahip olmaları nedeniyle dünya çapında sıklıkla kullanılan antibiyotikler arasındadır. Yaygın ... -
Effect of agomelatine on intestinal smooth muscle contractility in rats
(İnönü Üniversitesi Tıp Fakültesi, 2022)Aim: The purpose of the present study was to investigate in vitro the effect of agomelatine, an analog of melatonin, on potassium chloride-stimulated contractions (KCl) in duodenum, jejunum, ileum, and colon in ... -
Rutin mikrobiyoloji laboratuvarlarında bulunan temel besiyerlerinde trichomonas vaginalis’in üretilmesi
(Galenos Yayınevi, 2022)Amaç: Trichomonas vaginalis, tek hücreli ve kamçılı bir parazit olup, cinsel yolla bulaşan etkenler arasında virüslerden sonra en sık görülen ikinci patojendir. T. vaginalis’in laboratuvar tanısı, mikroskobik inceleme, ... -
Investigation the effect of ramelteon on urinary bladder smoth muscle contraction-relaxation mechanism
(İnönü Üniversitesi Tıp Fakültesi, 2022)Aim: A melatonin receptor agonist ramelteon is a drug that is also used in urinary tract infections. Melatonin is known to have an effect on smooth muscle contraction. In this study, we aimed to question whether ramelteon ... -
Retrospective evaluation of gastrointestinal system infections: Investigation of viral, bacterial, and parasitic etiological agents
(İnönü Üniversitesi Tıp Fakültesi, 2022)Aim: We aimed to retrospectively investigate the viral, bacterial, and parasitic etiological agents detected in patients to present with gastrointestinal complaints and examine their distribution in our region. Materials ... -
Erianin, a promising agent in the treatment of glioblastoma multiforme triggers apoptosis in U373 and A172 glioblastoma cells
(Inst Bioloska Istrazivanja Sinisa Stankovic, 2022)Glioblastoma is an aggressive, common and deadly primary intracranial brain tumor in adults. The antitumor activity of erianin, a dibenzyl compound found in Dendrobium chrysotoxum Lindl. extract, has not been previously ... -
Repeated acetaminophen administration damaged hippocampal tissue but did not affect prefrontal cortex or anxiety behaviors
(Nencki Inst Experimental Biology, 2022)Acetaminophen is one of the most widely used over-the-counter drugs worldwide for the treatment of pain and fever. Although acetaminophen use is known to impair hippocampus-related learning and memory, its effect on anxiety ... -
Radioanatomical overview of carpal tunnel syndrome
(Carbone Editor, 2022)Introduction: This study aims to investigate the Carpal Tunnel Syndrome (CTS) levels of the patients predi-agnosed with CTS by electromyography (EMG) by using the scanning model. Materials and methods: The study included ... -
Glutamate receptor antagonist suppresses the activation of nesfatin-1 neurons following refeeding or glucose administration
(Via Medica, 2022)Background: Nesfatin-1 is a newly identified satiety peptide that has regulatory effects on food intake and glucose metabolism, and is located in the hypothalamic nuclei, including the supraoptic nucleus (SON). In this ... -
Expression of the ionotropic glutamate receptors on neuronostatin neurons in the periventricular nucleus of the hypothalamus
(Via Medica, 2022)Background: Neuronostatin, a newly identified peptide, is accepted as an anorex- igenic peptide since it suppresses food intake when given intracerebroventricularly. Although the effect mechanisms of neuronostatin have ... -
Ubiquitin-specific protease 8 gene expression in sporadic pituitary adenomas
(Maghira & Maas Publications, 2022)OBJECTIVES: In sporadic pituitary adenomas, the role of Ubiquitin-specific protease 8 (USP8) is not clearly defined. Mutations in USP8 gene are known to influence formation of the corticotroph adenomas. However, it has not ... -
The clinical significance of anti-DFS70 autoantibodies and its correlation with vitamin d levels
(Kare Publ, 2022)OBJECTIVE: This study aims to investigate the clinical significance of anti-dense fine speckled 70 (DFS70) autoantibodies and its association with systemic autoimmune rheumatic diseases (SARD) related autoimmune markers ... -
Asprosin, a novel therapeutic candidate for painful neuropathy: An experimental study in mice
(Springer, 2022)Recent studies indicate presence of a strong link between adipokines and neuropathic pain. However, the effects of asprosin, a novel adipokine, on neuropathic pain have not been studied in animal models. Mouse models were ... -
A combination of ketogenic diet and voluntary exercise ameliorates anxiety and depression-like behaviors in Balb/C mice
(Elsevier Ireland Ltd, 2022)The positive effects of both ketogenic diet (KD) and regular voluntary exercise on anxiety and depression behavior have been recently reported in rodent animals, but the effects of pairing a KD with exercise on depression ... -
Low-intensity low-frequency pulsed ultrasound ameliorates sciatic nerve dysfunction in a rat model of cisplatin-induced peripheral neuropathy
(Nature Portfolio, 2022)Chemotherapy-induced peripheral neuropathy is a neurological complication that frequently occurs during chemotherapeutic intervention, resulting in damaged myelin sheath, motor weakness and/or sensory impairment. This study ... -
Evaluation of the effects of systemic irisin hormone application on osseointegration of titanium implants: An experimental study
(Lippincott Williams & Wilkins, 2022)This study aimed to conduct a biomechanical investigation of the effects of systemic irisin hormone application on the osseointegration of titanium implants in rat tibias. After surgical implementation of titanium implants ... -
Morphometric evaluation of sacrum volume in healthy women
(Wolters Kluwer Medknow Publications, 2022)The aim of this study was to calculate volume of the sacrum, sacral canal, caudal part of the epidural space, and dural sac volumes using stereological methods on magnetic resonance images (MRIs). Material and Methods: ... -
Serological interpretation of rheumatic manifestations in brucellosis
(Coll Physicians & Surgeons Pakistan, 2022)Objectives: To investigate the profile of autoimmune markers and to evaluate the status of vitamin D in the autoimmune process in brucellosis. Study Design: Descriptive study. Place and Duration of Study: Department of ... -
Neutrophil/lymphocyte and platelet/lymphocyte ratios as a biomarker in postoperative wound infections
(Walter De Gruyter GMBH, 2022)Objectives We aimed to investigate retrospectively the association between the development of surgical wound infection after orthopedic surgery, and neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) ...
