Güncel Gönderiler: Temel Tıp Bilimleri
Toplam kayıt 319, listelenen: 41-60
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Effects of Romanian student's awareness and needs regarding plastic waste management
(MDPI, 2023)The purpose of this study is to examine the effects of needs and awareness of university students on their environmental behaviour. With this purpose the data was collected from 537 students from the University of Cluj ... -
The effect of darbepoetin alpha on anxiety in a neuroinflammation-induced rat model
(Wiley, 2023)Özet bilgisi yok. -
Hyperarc Vmat and Vmat planning for stereotactic radiosurgery in multiple brain metastases
(Elsevier, 2023)Automated treatment planning systems are available for linear accelerator (LINAC) based single and more isocenter multitarget stereotactic radiosurgery (SRS) of brain metastases. HyperArc Volumetric Modulated Arc Therapy ... -
The effects of irisin hormone on seminal vesicle fluid in male rats administered paroxetine
(Wiley, 2023)It is known that antidepressants cause some negative effects in the reproductive system and especially in sperm parameters. It is stated that exercise is an effective factor on the transition to puberty, reproductive ... -
AGR2 gene expression in glioblastoma: A novel molecular potential target for diagnosis and treatment
(Turkish Neurosurgical Society, 2023)AIM: To assess anterior gradient protein 2 (AGR2) gene expression in patients with human glioblastoma (GBM) in comparison to levels in healthy brain tissues. MATERIAL and METHODS: We evaluated the expression levels of AGR2 ... -
Effects of chronically exogenous oxytocin on ovary and uterus: A comparison of intraperitoneal and intranasal administration
(Elsevier, 2023)Oxytocin (OT) has been studied as a therapeutic neuropeptide in various diseases, but its effect on the ovary and uterus is not fully known. This study investigates the effects of intranasal and intraperitoneal OT ... -
Erianin as a promising novel agent in the treatment of neuroblastoma: The anti-cancer effects and underlying molecular mechanisms
(Bentham Science Publishers, 2023)Background: Erianin is an active dibenzyl compound isolated from Dendrobium officinale and Dendrobium chrysotoxum and there are very few studies on molecular mechanisms and drug targets of erianin. In addition, there is ... -
Investigation of the anticancer mechanism of monensin via apoptosis-related factors in SH-SY5Y neuroblastoma cells
(Wiley, 2023)Monensin is an ionophore antibiotic that inhibits the growth of cancer cells. The aim of this study was to investigate the apoptosis-mediated anticarcinogenic effects of monensin in SH-SY5Y neuroblastoma cells. The effects ... -
Modulation of melatonin receptors regulates reproductive physiology: The impact of agomelatine on the estrus cycle, gestation, offspring, and uterine contractions in rats
(Acad Sciences Czech Republic, 2023)Agomelatine is a pharmaceutical compound that functions as an agonist for melatonin receptors, with a particular affinity for the MT1 and MT2 receptor subtypes. Its mode of action is integral to the regulation of diverse ... -
A cross-cultural analysis for plastic waste perception of students from Romania and Turkey
(MDPI, 2023)The article brings to attention a cross cultural model related to the perception of students in relation to the current problem of plastic waste. To create the model, a questionnaire was applied online in two countries at ... -
Treadmill exercise improves behavioral and neurobiological alterations in restraint-stressed rats
(Springer Nature, 2023)Stress is a state that is known to impact an organism's physiological and psychological balance as well as the morphology and functionality of certain brain areas. In the present work, chronic restraint stress (CRS) model ... -
Development and validation of liquid chromatography/stable isotope-dilution tandem mass spectrometry method for measurement of dexamethasone, total cortisol and free cortisol in human plasma
(Dokuz Eylul Univ Inst Health Sciences, 2023)Background Cortisol plays a role in the regulation of metabolic homeostasis. Dexamethasone is a powerful synthetic glucocorticoid that acts as an anti-inflammatory and immunosuppressive agent. Plasma free cortisol, which ... -
Therapeutic potential of mesenchymal stem cell-derived conditioned medium for diabetes mellitus and related complications
(Wiley, 2023)Diabetes mellitus (DM) is one of the most life-threatening metabolic disorders, with 9% of the global prevalence, and it is estimated to be rising to 12.2% in 2045. Currently, there is no definitive treatment for DM. ... -
Protective effect of pomegranate juice on lead acetate-induced liver toxicity in male rats
(Pera Yayıncılık Hizmetleri, 2023)Objective: Lead has been reported to cause oxidative stress in liver tissues and cause histopathological changes. Studies have shown that pomegranate juice has antioxidant properties that prevent oxidative stress. In this ... -
Effects of conditioned mediums collected from 2d or 3d cultured mscs on kidney functions of rats with autoimmune diabetes induced with streptozocin
(Oxford Univ Press, 2023)Background and Aims: The main mechanism of therapeutic action of mesenchymal stem cells (MSCs) could be resulted from their secretome content rather than their direct differentiation into damaged cells [1, 2]. Preconditioning ... -
Effects of monensin and rapamycin combination therapy on tumor growth and apoptosis in a xenograft mouse model of neuroblastoma
(MDPI, 2023)Neuroblastoma is the most common pediatric solid tumor originating from the neural crest. New treatment options are needed to improve treatment outcomes and the survival of patients with neuroblastoma. Monensin is an ... -
The relationship of circulating MOTS-c level with liver fibrosis and metabolic components in patients with metabolic dysfunction-associated fatty liver disease
(Verduci Publisher, 2023)OBJECTIVE: Mitochondrial open reading frame of the 12s ribosomal RNA type-c (MOTS-c) is a novel identified mitochondrial signal transmission peptide that plays an important role in glucose, amino acid and lipid metabolism. ... -
The frequency of thyroid dysfunction in patients with a diagnosis of depressive disorder
(Wolters Kluwer Medknow Publications, 2023)Objective: Thyroid dysfunctions are among the most common endocrine disorders in society. An increase or decrease in thyroid hormone levels may present with neurological and/or psychiatric symptoms. In this study, we aimed ... -
Evaluation of volumetric asymmetry of the dorsolateral prefrontal cortex and medial temporal lobe in Alzheimer's disease using the atlas-based method
(Lippincott Williams and Wilkins, 2023)Brain areas affected during neurodegenerative disease progression are considered anatomically connected to the first affected areas. The dorsolateral prefrontal cortex (DLPFC) has connections with the medial temporal lobe ... -
Investigation of the TLR4 and IRF3 signaling pathway-mediated effects of monensin in colorectal cancer cells
(Springer, 2023)Monensin is an ionophore antibiotic isolated from Streptomyces cinnamonensis with very strong antibacterial and antiparasitic effects. Although monensin is known to exhibit anticancer activity in different cancer types, ...
