Yazar "Tok, Tuğba Taşkın" için Moleküler Biyoloji ve Genetik-Makale Koleksiyonu listeleme
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Prodrugs for nitroreductase based cancer therapy-2: Novel amide/Ntr combinations targeting PC3 cancer cells
Güngör, Tuğba; Önder, Ferah Cömert; Tokay, Esra; Gülhan, Ünzile Güven; Hacıoğlu, Nelin; Tok, Tuğba Taşkın; Çelik, Ayhan; Köçkar, Feray; Ay, Mehmet (Elsevier France-Editions Scientifiques Medicales Elsevier, 2019)The use of nitroreductases (NTR) that catalyze the reduction of nitro compounds by using NAD(P)H in GDEPT (Gene-directed enzyme prodrug therapy) studies which minimize toxicity at healthy cells and increases concentration ... -
Prodrugs for nitroreductase-based cancer therapy-3: Antitumor activity of the novel dinitroaniline prodrugs/Ssap-NtrB enzyme suicide gene system: Synthesis, in vitro and in silico evaluation in prostate cancer
Tokay, Esra; Güngör, Tuğba; Hacıoğlu, Nelin; Önder, Ferah Cömert; Gülhan, Ünzile Güven; Tok, Tuğba Taşkın; Çelik, Ayhan; Ay, Mehmet; Köçkar, Feray (Elsevier France-Editions Scientifiques Medicales Elsevier, 2020)Prodrugs for targeted tumor therapies have been extensively studied in recent years due to not only maximising therapeutic effects on tumor cells but also reducing or eliminating serious side effects on healthy cells. This ...
