Protective effects of an extract of propolis in scopolamine-induced cognitive impairment in rats

Abstract

Purpose: Propolis is a natural substance collected by honeybees from buds and exudates of certain trees which has antioxidant, antibacterial, antiviral and anti-inflammatory and neuroprotective effect in neurodegenerative disorders including Alzheimer’s disease(AD). However, in vivo effect of propolis in scopolamine (SC)-induced cognitive impairment in emotional and spatial memory testing models is not well evaluated. Therefore, the present neurobehavioral study was undertaken to evaluate the effects of propolis on SC-induced cognitive impairment in rats.