Prognostic nutritional index as a predictor of no-reflow occurrence in patients with st-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention

Abstract

Nutritional status and its index (Prognostic Nutritional Index, PNI) is an important prognostic factor for ST-segment elevation myocardial infarction (STEMI). The present study investigated whether PNI it is associated with no-reflow in patients with STEMI. In this retrospective study, 404 patients with STEMI and underwent primary percutaneous coronary intervention (pPCI) were consecutively included, between January 2016 and December 2018. No-reflow phenomenon (NRP) was detected in 103 (25.4%) patients. In multivariate logistic regression analysis C-reactive protein (CRP) (odds ratio (OR): 1.693, 95% confidence interval (CI): 1.126–2.547, P =.011), left ventricle ejection fraction (LVEF) (OR: 0.777, 95% CI: 0.678–0.891, P <.001), SYNTAX score (OR: 1.114, 95% CI: 1.050–1.183, P =.001), low density lipoprotein cholesterol (LDL-C) (OR: 1.033, 95% CI: 1.013–1.055, P =.002), hemoglobin level (OR: 0.572, 95% CI: 0.395–0.827, P =.003), PNI (OR: 0.554, 95% CI: 0.448–0.686, P <.001) were associated with NRP. The area under curve of PNI was significantly higher than albumin (z = 4.747, P <.001) and lymphocyte values (z = 3.481 P <.001). PNI was associated with no-reflow occurrence and mortality. So, PNI may be useful to predict NRP risk in patients with STEMI before pPCI.