Seizures as a rare but serious adverse effect of leukotriene receptor

Abstract

Leukotriene receptor antagonists (LTRAs) are used widely in the treatment of allergic rhinitis and asthma in children.1,2 LTRAs are safe in combination with antihistamines in patients with chronic urticaria who respond inadequately to antihistamines alone.3 Several clinical trials have emphasized that LTRAs can be considered safe. Nevertheless, many adverse effects associated with LTRAs have been reported. Most of the adverse events are mild (headache, gastrointestinal disorders, pharyngitis, fatigue, upper respiratory tract infection, cutaneous rash, and reversible changes in the serum transaminase levels).