A gender-based analysis of disease activity and ıts relationship with anxiety, depression, fatigue, and fibromyalgia in psoriatic arthritis

Abstract

Background/Purpose : This study sought to compare the disease activity and its relationship with anxiety, depres-sion, fatigue, and  bromyalgia of patients with psoriatic arthritis (PsA) between female and male gender in a Turkish population. Methods : This multi- center Turkish League Against Rheumatism (TLAR) Network study included 1134 patients (726 females, 408 males) diagnosed with PsA according to the CASPAR criteria. Demographic and clinic parameters of the patients were recorded. Disease activity was evaluated using the scores of DAS28, DAPSA, cDAPSA, MDA, VLDA, and BASDAI. Health Assessment Questionnaire (HAQ), SF- 36, Hospital Anxiety and Depression Scale (HAD), fatigue VAS (0- 10), and Fibromyalgia Rapid Screening Tool (FIRST) were assessed. Disease activity and remission rates were compared in male and female patients, and their relationship with fatigue, anxiety, depression, and  bromyal-gia scores was analyzed. The Spearman correlation coef cient was used to assess correlations. Comparisons were made using the Mann- Whitney U and chi- squared tests. p< 0.05 was considered signi cant.