Examination of hemorheological and exerkine concentrations at four-week whole body vibration exercise in obese women: A pilot study

Abstract

Background Obesity can result in increased visceral adipose tissue, insulin resistance, and impaired fasting glucose. Objective The aim of the study was to investigate the acute and chronic effects of WBVE on erythrocyte deformability, plasma viscosity, total oxidant/antioxidant status (TOS/TAS), oxidative stress index (OSI) and serum exerkine levels in obese women. Methods The study comprised 13 obese women (mean age 41.32 +/- 5.26 years, BMI 34.18 +/- 1.67 kg/m2). Participants performed exercises using a vibration device for 12 sessions. Erythrocyte deformability (ektacytometry), plasma viscosity (rotational viscometry), plasma TOS/TAS, OSI and serum irisin, visfatin and resistin concentrations (ELISA) were evaluated. Blood samples were collected before and after the exercise at the first and fourth weeks. Results Erythrocyte deformability values were increased after single session of WBVE at shear stress of 0.30 and 9.49 Pa and decreased after single session of WBVE at shear stress of 16.87 and 30 Pa (p < 0.05) at the first week. However, after 4 weeks of WBVE, erythrocyte deformability at 0.30 and 0.53 Pa increased; TOS, OSI and plasma viscosity were all decreased (p < 0.05). Serum irisin and resistin levels significantly increased after 4 weeks of WBVE (p < 0.05), whereas visfatin did not show statistically significant changes (p > 0.05). Conclusions Four weeks of WBVE significantly improved the erythrocyte deformability, oxidative stress, plasma viscosity, and serum levels of irisin and resistin in obese women.