The ratio of fibrinogen to albumin as a predictor of contrast-induced nephropathy after carotid angiography: Reply

Abstract

We would like to thank Cetin et al for their interest in our article.1 As stated in their letter,2 we found that the fibrinogen to albumin ratio was associated with contrast-induced nephropathy (CIN) after carotid angiography.1 Low serum albumin level has been shown to be related to cardiovascular morbidity and mortality.3,4 The mechanism of the association of low albumin and CIN is not clear. Some possible mechanisms are oxidative stress and increased inflammatory status.5,6 Also, its reduced level may lead to the increased blood viscosity which is associated with endothelial dysfunction that may contribute to the development of CIN.7