Ischemia-modified albumin levels as a biomarker of ischemic injury in dogs with parvoviral enteritis

Abstract

The aim of this study was to determine ischemia-modified albumin levels in dogs with parvoviral enteritis. The study was carried out on a total of 24 dogs, 16 with parvoviral enteritis (sick group) and 8 healthy (control group). The diagnosis of parvoviral enteritis was made by clinical findings, immunochromatographic rapid diagnostic kit, and PCR analysis of stool samples. For blood analysis, 3 ml of blood was collected from the cephalic vein of dogs into tubes without anticoagulant prior to treatment. The tubes were maintained at room temperature for 30 minutes, before which they were centrifuged at 5000 rpm for 5 minutes. Serum samples were then extracted and stored at -20°C until further analysis. While IMA, IMAR, and cTn I levels and capillary refill time were significantly higher in dogs with parvoviral enteritis than in healthy dogs (P<0.05), albumin levels were significantly lower (P<0.05). As a result, it was observed that cardiac damage developed in dogs with par-voviral enteritis, and it would be useful to evaluate IMA and IMAR levels in the evaluation of ischemic damage.