Zizyphus jujuba as an antilipemic and antidiabetic agent in chronic kidney disease patients

Abstract

Introduction and Aims: Zizyphus jujuba, an oriental traditional medicine, have been widely used as a hypoglycemic and antilipemic agent. Study in rats showed that Z. jujuba is an effective and safe treatment for diabetes and dyslipidemia. It reduce the glucose, cholesterol, triglyceride, LDL (low-density lipoprotein) and increase the HDL (high-density lipoprotein), and insulin levels. Administration of Z.jujuba has no toxic effect on kidney or liver in rats.However, little study is available on its effects in humans, and no data about the effect in chronic kidney disease (CKD) patients. In this study, the potential effect of Z. jujuba on plasma glucose and lipid levels were investigated in CKD patients.