Synthesis, complexation and antifungal, antibacterial activity studies of a new macrocyclic Schiff base

Abstract

A new macrocyclic ligand, L was synthesized using the high dilution condition with condensation of triethylene glycol diamine and terephtalaldehyde in ethanol. The obtained product, L was identified by FTIR, H-1-NMR, C-13-NMR and Mass spectroscopy. The extraction equilibrium constants were estimated using dichloromethane/water membranes transfer with ICP-AES. and AES spectroscopy. Biological studies of this compound was determinated with disc diffusion method. The biological activity results showed that the synthesized ligand L has high activity against the studied microorganisms and high complexation ability against the Fe2+ cation.