Orexins cause epileptic activity
| dc.authorid | 0000-0002-7884-5623 | en_US |
| dc.contributor.author | Erken, Haydar Ali | |
| dc.contributor.author | Erken, Gülten | |
| dc.contributor.author | Genç, Osman | |
| dc.contributor.author | Kortunay, Selim | |
| dc.contributor.author | Şahiner, Melike | |
| dc.contributor.author | Turgut, Günfer | |
| dc.contributor.author | Turgut, Sebahat | |
| dc.date.accessioned | 2019-10-17T11:37:31Z | |
| dc.date.available | 2019-10-17T11:37:31Z | |
| dc.date.issued | 2012 | en_US |
| dc.department | Fakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü | en_US |
| dc.description | Erken, Gülten (Balikesir Author) | en_US |
| dc.description.abstract | Orexins have been implicated in the regulation of sleep-wake cycle, energy homeostasis, drinking behavior, analgesia, attention, learning and memory but their effects on epileptic activity are controversial. We investigated whether intracortical injections of orexin A (100 pmol) and B (100 pmol) cause epileptic activity in rats. We observed epileptic seizure findings on these two groups rats. Orexin A and B also significantly increased total EEG power spectrum. Our findings indicate that orexins cause epileptic activity. | en_US |
| dc.description.sponsorship | Pamukkale University | en_US |
| dc.identifier.doi | 10.1016/j.peptides.2012.06.012 | |
| dc.identifier.endpage | 164 | en_US |
| dc.identifier.issn | 0196-9781 | |
| dc.identifier.issn | 1873-5169 | |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.scopus | 2-s2.0-84865244135 | |
| dc.identifier.scopusquality | Q2 | |
| dc.identifier.startpage | 161 | en_US |
| dc.identifier.uri | https://doi.org/10.1016/j.peptides.2012.06.012 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12462/8630 | |
| dc.identifier.volume | 37 | en_US |
| dc.identifier.wos | WOS:000308899100023 | |
| dc.identifier.wosquality | Q2 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.language.iso | en | en_US |
| dc.publisher | Elsevier Science Inc | en_US |
| dc.relation.ispartof | Peptides | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
| dc.subject | EEG | en_US |
| dc.subject | Epilepsy | en_US |
| dc.subject | Hypocretin | en_US |
| dc.subject | Orexin | en_US |
| dc.subject | Power Spectrum | en_US |
| dc.subject | Seizure | en_US |
| dc.title | Orexins cause epileptic activity | en_US |
| dc.type | Article | en_US |
