Serum salusin-alpha and salusin-beta levels in patients with psoriasis

Abstract

Salusin is a bioactive peptide, discovered by Shichri et al.[1] in 2003. This multifunctional bioactive peptide is present in blood, urine and tissues in two forms: salusin-α and salusin-β. Salusins have important effects on the cardiovascular system. In particular, salusin-β is the most potent hypotensive peptide and has a vasodilator effect. This peptide induces hypotension, bradycardia and cardiac dysfunction through a cholinergic mechanism.