SARS-CoV-2 (Covid-19): Interferon-epsilon may be responsible of decreased mortality in females

Abstract

Covid-19 disease which started in Wuhan, China has became a pandemic now (Ahn et al., 2020). According to descriptive analysis in different populations, it seems that males have higher mortality than females (Guan et al., 2020; Livingston and Bucher, 2020; Grasselli et al., 2020). We want to argue about this fact according to the reservoir of the virus and by discussing about interferon (IFN) epsilon (ε).