Evaluation of new chalcone derivatives as polyphenol oxidase inhibitors

Basit Öğe Kaydı
dc.authorid0000-0001-7092-8857en_US
dc.contributor.authorSönmez, Fatih
dc.contributor.authorSevmezler, Sedat
dc.contributor.authorAtahan, Alparslan
dc.contributor.authorCeylan, Mustafa
dc.contributor.authorDemir, Dudu
dc.contributor.authorGençer, Nahit
dc.contributor.authorArslan, Oktay
dc.contributor.authorKüçükislamoğlu, Mustafa
dc.date.accessioned2019-10-16T11:25:16Z
dc.date.available2019-10-16T11:25:16Z
dc.date.issued2011en_US
dc.departmentFakülteler, Fen-Edebiyat Fakültesi, Kimya Bölümüen_US
dc.descriptionDemir, Dudu (Balıkesir Author)en_US
dc.description.abstractA newly series of 4-(phenylurenyl) chalcone (4a-j) and 4'-(phenylurenyl/thiourenyl)chalcone (9a-l) derivatives were synthesized and their inhibitory effects on the diphenolase activity of banana tyrosinase were evaluated. Tyrosinase has been purified from banana on an affinity gel comprised of Sepharose 4B-L-tyrosine-p-aminobenzoic acid. The result showed that 4a-j inhibited the PPO enzyme activity. Conversely, 9a-h and 9i-l showed activator effect on tyrosinase enzyme activity.en_US
dc.identifier.doi10.1016/j.bmcl.2011.09.130
dc.identifier.endpage7482en_US
dc.identifier.issn0960-894X
dc.identifier.issue24en_US
dc.identifier.scopus2-s2.0-81255205266
dc.identifier.scopusqualityQ2
dc.identifier.startpage7479en_US
dc.identifier.urihttps://doi.org/ 10.1016/j.bmcl.2011.09.130
dc.identifier.urihttps://hdl.handle.net/20.500.12462/7076
dc.identifier.volume21en_US
dc.identifier.wosWOS:000297150600048
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofBioorganic & Medicinal Chemistry Lettersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChalconesen_US
dc.subjectTyrosinase InhibitorIen_US
dc.titleEvaluation of new chalcone derivatives as polyphenol oxidase inhibitorsen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket

Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
nahit-GENCER.pdf
Boyut:
298.51 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Lisans paketi

Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Kimya-Makale Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WOS İndeksli Yayınlar Koleksiyonu