Effect of Z technique application on patient comfort, pain and adverse events in allergic rhinitis patients receiving subcutaneous allergen immunotherapy: A randomized controlled study

Abstract

Objective: This study aims to determine the effect of the Z technique on patient comfort, pain, and adverse events in allergic rhinitis patients receiving subcutaneous allergen immunotherapy (SCIT). Method: This study employed a randomized controlled trial with a pre-test and post-test design. A total of 60 participants were randomly assigned to either the experimental group (Z technique, n=30) or the control group (conventional SCIT method, n=30). Data were collected using the personal information form, the visual analog scale for pain, the general well-being scale, and the adverse events form (swelling, redness, medication leakage). Data were analyzed using IBM SPSS Statistics, with Pearson’s chi-square test, independent t-test, dependent t-test, and McNemar’s test applied for statistical evaluation. Trial Registration: ClinicalTrials.gov. Identifier: NCT05657262. Results: SCIT using the Z technique significantly improved quality of life, reduced pain levels, and minimized adverse events after one hour and one dayat 1 hour and 1 day (p<0.05). Conclusion: The Z technique enhanced patient comfort, decreased pain perception, and reduced adverse events, making it a promising alternative for SCIT administration.