Güncel Gönderiler: Moleküler Biyoloji ve Genetik Bölümü
Toplam kayıt 114, listelenen: 81-100
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TGF-Beta upregulates URG-4/URGCP gene expression in Hepatoma cells
(Wiley-Blackwell, 2015)URG-4/URGCP has been found to contribute importantly tomultistep carcinogenesis. Over-expression of URG4/URGCPaccelerated tumor development in nude mice and also induced insome cancer cell types such as hepatocellular ... -
Transcription of the PSMD4 gene is upregulated in hypoxia in prostate cancer cells
(Wiley-Blackwell, 2015)ThePSMD4(Proteosome 26S non-ATPase subunit 4) gene islocated human chromosome 1. This gene encodes three proteins,namely S5A, antisecretory factor (ASF) and Angiocidin. S5a isthe polyubiquitin binding subunit of the 26S ... -
Transactivation of the human adamts-2 gene promoter through proinflammatory cytokine tnf-alpha in osteoblast-like cells
(Wiley-blackwell, 2015)TNF-ais a proinflammatory cytokine produced by numerous celltypes, including macrophages, lymphocytes, fibroblasts and kerat-inocytes in response to inflammation, infection and other envi-ronmental stresses. TNF-ahas ... -
Genetic mechanism of oleocanthal biosynthesis in olive
(Wiley-Blackwell, 2016)Oleocanthal is an important secondary metabolite that has beenreported to be useful against important human diseases includingcancer. The aim of this study was to identify and characterize thekey biochemical and genetic ... -
Evaluation of the genotoxic potential of some nanocomposites by comet assay
(Wiley-Blackwell, 2016)Due to its similar nature to the bone, nanohydroxyapatite is abiocompatible particle and poly(methyl methacrylate) (PMMA)is a polymer that has been used in dentistry and orthopedicapplications for years. In this study, ... -
Bioinformatic analysis and molecular characterization of ethylene-responsive transcription factor RAP2-12 from olive
(Wiley-Blackwell, 2016)Ethylene-responsive transcription factorRAP2-12is associatedwith ethylene-response, activation of hypoxic gene and hypoxiatolerance of plants. Under normal aerobic conditions it localizesto the plasma membrane but under ... -
Isolation and characterization of genetic elements related to periodicity and fruit detachment in olive
(Wiley-Blackwell, 2016)Periodicity and difficult fruit detachment in olive cause significantyield loss for olive growers. These features greatly differ fromcultivar to cultivar pointing the genetic factors’ roles with theseprocesses. The objective ... -
The effect of sodium perborate tetrahydrate some antioxidant enzyme activities
(Wiley-Blackwell, 2016)One of the boron compounds is sodium perborate tetrahydrate(NaBO3.4H2O), which the most widely used solid peroxygencompounds. It is used in safety bleach formulations, detergentsand tooth powders. As known these products ... -
Is thymoquinone promising anticancer agent in hepatoma cell line?
(Wiley-Blackwell, 2016)The biological activity ofNigella sativaseeds is mainly attributedto its essential oil component which is pre-dominantly (30–48%)thymoquinone (TQ). Therapeutic effect of TQ was exhibited inmany diseases including inflammation, ... -
Isolation and characterization of an olive splicing factor 3B subunit 1
(Wiley-Blackwell, 2016)Splicing factor 3B subunit 1 (SF3B1) functions in the regulationof translation and gene expression. SF3B1 forms U2 smallnuclear ribonucleoprotein complex (U2 snRNP). Splicing factors3A and 3B binds pre-mRNA at the 50site ... -
Isolation and characterization of the ribosomal L1 protein from olive
(Wiley-Blackwell, 2016)Despite as a ribosomal protein, L1 is known as the inhibitor ofthe cellular aging gene and it has been reported to have roles inapoptosis. The ribosomal L1 protein is larger than the LSU ofribosome and contains 2 domains ... -
Isolation and molecular molecular characterization of VPS39/VAM6 from olive
(Wiley-Blackwell, 2016)VPS39/VAM6 promotes aggregating and fusing of endosomesand lysosomes. It is a component of a protein complex that isfound in vacuole membranes. This gene has been studied fromvarious organisms including humans,Drosophila ... -
Molecular characterization of an olive imidazoleglycerol-phosphate dehydratase
(Wiley-Blackwell, 2016)Imidazoleglycerol-phosphate dehydratase (IGPD) catalyzes the6th step in histidine biosynthesis in various organism includingfungi, bacteria and plants. There are two different isoforms ofIGPD; IGPD1 and IGPD2. By finding ... -
Molecular analysis of serine/arginine rich SC35 splicing factor from olive
(Wiley-Blackwell, 2016)Olive (Olea europaeaL.) is an evergreen fruit tree adapted toMediterranean climate and rich in tannins, essential oils andorganic acids. Serine/arginine rich splicing factors are essential inseqeunce specific splicing of ... -
Isolation and characterization of a hexose converter from olive
(Wiley-Blackwell, 2016)Introduction:Hexose sugars are key components of glycolysisand photosynthesis. The genes regulating their conversion intoone another, is therefore, of great importance for the control ofcarbon metabolism. In this study, ... -
PEG/Ganoderma lucidum biocomposites
(Wiley-Blackwell, 2016)Composite material is a multi-phase system consisted of matrixmaterial and reinforcing material. Matrix material is a continu-ous phase and reinforcing material is a dispersed phase. Themain two bioactive components ... -
Preparation, characterization and some biological properties of PVP/Ganoderma lucidum composites
(Wiley-Blackwell, 2016)Polyvinylpyrrolidone (PVP) is a biodegradable material and natu-ral polymeric biomaterial in such studies.Ganoderma lucidumis anatural material containing triterpenes, polysaccharides, adeno-sine, polypeptides, and amino ... -
Proliferative effect of hypericine on human skin fibroblast cells and identification of the mechanism of action in molecular level
(Wiley-Blackwell, 2016)Hypericine is traditionally used as a wound healing agent. There-fore it is a potential promoter for reprogramming inducedpluripotent stem cells (IPSCs) which posses several problems due to drawbacks associated with ...
