Güncel Gönderiler: Tıp Fakültesi
Toplam kayıt 1740, listelenen: 81-100
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Investigation of patients with childhood epilepsy in single center: Comprehensive genetic testing experience
(Wiley, 2024)Introduction: Epilepsy is a common multifactorial neurological disease usually diagnosed during childhood. In this study, we present the contribution of consecutive genetic testing to the genetic diagnostic yield of childhood ... -
Changes in paraoxonase, β-glucosidase, and carbonic anhydrase enzymes related to age and scopolamine-induced memory impairment in rats
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)This study aimed to investigate the changes in Paraoxonase (PON), Carbonic Anhydrase (CA), and β-glucosidase levels of different aged rats and scopolamine-induced memory impairment rats. This study used young, adult, and ... -
Early maladaptive schemas in autogenous and reactive subtypes of obsessive–compulsive disorder
(Taylor and Francis, 2024)Aims: The aim of this study is to identify early maladaptive schemas in patients with obsessive–compulsive disorder (OCD) and to determine the use of these schemas in OCD autogenous and reactive subtypes. Methods: The study ... -
In vitro and in silico investigations of the pro-apoptotic activity of Opuntia ficus-indica cladode extracts against K562 cells
(Walter De Gruyter GMBH, 2024)Objectives: Cladodes of Opuntia ficus-indica (OFI) are thought to be an excellent source of bioactive compounds, making them an aspirant for the manufacture of health-promoting compounds. This study aims at exploring the ... -
Could hepcidin be a new biomarker in patients with idiopathic pulmonary fibrosis (IPF)?
(MDPI, 2024)Hepcidin is a biomarker produced by hepatocytes in chronic disease anemia and is known to increase during chronic inflammation. This study compares the hepcidin levels in idiopathic pulmonary fibrosis (IPF) patients and ... -
Natural disasters as a maternal prenatal stressor and children's neurodevelopment: A systematic review
(MDPI, 2024)The intrauterine period is a time of high sensitivity in the development of the embryo and the fetus. Therefore, low levels of maternal stress are closely associated with healthy brain development in the neonatal and ... -
Effects of chronic intermittent cold stress on anxiety-depression-like behaviors in adolescent rats
(Elsevier, 2024)Stress, which triggers numerous physiological and behavioral responses in the organism, is a significant risk factor that contributes to the development of psychiatric disorders such as depression and anxiety. This study ... -
Effects of ozone disc nucleolysis in management of herniated lumbar intervertebral disc: A retrospective single-center study of 149 patients
(International Scientific Information, 2024)Background: Lower back pain is a common problem in the general population. Medical treatment is the first choice for patients without severe pain and major motor weakness. If patients do not benefit from conservative ... -
Predictors of acute kidney injury in chronic kidney disease patients treated for cardiovascular disease in the cardiac intensive care unit (MORCOR‑TURK subgroup analysis)
(Springer Heidelberg, 2024)Background Acute kidney injury (AKI) is a common complication in chronic kidney disease (CKD) patients in the cardiac intensive care unit (cardiac ICU). In this study, we aimed to identify predictors of AKI in CKD patients ... -
Darbepoetin alpha has an anxiolytic and anti-neuroinflammatory effect in male rats
(BMC, 2024)Aims We aimed to investigate the anxiolytic effect of darbepoetin alpha (DEPO), an erythropoietin derivative, in a neuroinflammation model regarding different behaviors and biological pathways. Methods Forty adult male ... -
Effect of high-intensity interval training on self-care and anxiety-like behaviors in naive rats
(Springer, 2024)Self-care behavior covers individual's health, life and well-being to maintain the necessary activities. The aim of this study is to examine the self-care and possible anxiolytic efects of high-intensity interval exercise ... -
A multicenter randomized double-blind vehicle-controlled parallel group phase 2 study evaluating the efficacy and safety of gn-037 cream in patients with mild-to-moderate plaque psoriasis
(Adis İnt Ltd, 2024)IntroductionTopical therapies are used in almost all patients with psoriasis. A novel fixed topical combination cream (GN-037) with a lower concentration (0.0356%) of clobetasol 17-propionate (CP) was developed together ... -
Radiology findings in a case of acute methanol intoxication complicated with intracranial hemorrhage
(Balıkesir Üniversitesi, 2024)Objective: Methanol intoxication is rare and it can be fatal. This case report aimed to describe the radiological findings in acute methanol intoxication complicated with intracranial haemorrhage in a young patient. A ... -
Could the HALP score serve as a biomarker of bronchiectasis exacerbation?
(Tuba Yıldırım, 2024)Introduction: Bronchiectasis is a chronic inflammatory lung disease and patients may occasionally experience acute exacerbations. Our study aims to determine the relationship between exacerbation periods and HALP ... -
Stage at diagnosis of colorectal cancer in the Middle East and Northern Africa: A population-based cancer registry study
(Wiley, 2024)Colorectal cancer (CRC) is the 2nd most common cancer and 3rd most common cause of death in the Middle East and Northern Africa (MENA) region. We aimed to explore CRC stage at diagnosis data from population-based cancer ... -
Expanding the phenotypic and genotypic characteristics of trichohepatoenteric syndrome: A report of eight patients from five unrelated families
(Springer, 2024)Trichohepatoenteric syndrome (THES) is characterized by neonatal-onset intractable diarrhea. It often requires long-term total parenteral nutrition (TPN). In addition, other characteristic findings of the syndrome include ... -
Comparative analysis of effects of conditioned mediums obtained from 2D or 3D cultured mesenchymal stem cells on kidney functions of diabetic rats: Early intervention could potentiate transdifferentiation of parietal epithelial cell into podocyte precursors
(Elsevier, 2024)Aim: The secretome of mesenchymal stem cells (MSCs) could be a potential therapeutic intervention for diabetes and associated complications like nephropathy. This study aims to evaluate the effects of conditioned ... -
Effects of coenzyme Q10, fullerene C60, and αlpha-lipoic acid on histomorphometric, antiapoptotic and ınsulin expression in pancreatic tissue of rats exposed to bisphenol A
(Prof.Dr. Mustafa İssi, 2024)The aim of this study was to determine the morphometric changes in the pancreas, apoptosis related pancreatic damage, and differences in insulin expression in male rats exposed to low doses of BPA from early pubertal ... -
A case of mimicking normal pressure hydrocephalus in a female older patient: Coexistence of probable Alzheimer’s dementia and colpocephaly
(Routledge Journals, Taylor & Francıs Ltd, 2024)Colpocephaly, a cause of hydrocephalus, is characterized by disproportionately enlarged occipital horns of the lateral ventricles. It is rarely seen in the older adults. Few cases were reported as colpocephaly in elderly ... -
Evaluation of serum magnesium levels in patients with the diagnosis of depressive disorder applied to a psychiatry clinic: A retrospective study
(Balıkesir Üniversitesi, 2024)Objective: The role of magnesium in the pathophysiology of depression has increased the interest in magnesium. Therefore, in this study, we aimed to evaluate serum magnesium levels in patients diagnosed with depressive ...
