Güncel Gönderiler: Temel Tıp Bilimleri-Makale Koleksiyonu
Toplam kayıt 280, listelenen: 221-240
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The protective effects of caffeic acid phenethyl ester against toluene-induced nephrotoxicity in rats
(Sage Publications Inc, 2016)Caffeic acid phenethyl ester (CAPE) has antioxidant and anti-inflammatory properties. The aim of this study is to examine the negative effects of toluene on kidney tissues and functions and to investigate the protective ... -
Potential role of some oxidant/antioxidant status parameters in prefrontal cortex of rat brain in an experimental psychosis model and the protective effects of melatonin
(Verduci Publisher, 2014)OBJECTIVES: The etiology of schizophrenia is unknown. However, some of the neuropathological changes in schizophrenia may be the result of increased free radical-mediated or reactive oxygen species (ROS) mediated neurotoxicity. ... -
The melatonin attenuates alloxan ınduced post-diabetic testicular damage and oxidative effects in rats
(Kafkas Univ, 2015)The aim of this study was to examine the protective effect of melatonin (MLT) on the alloxan-induced post-diabetic testicular damage in rats. Forty-eight Sprague Dawley male rats were divided into four groups (n = 12). ... -
Effects of dietary boron and phytase supplementation on growth performance and mineral profile of broiler chickens fed on diets adequate or deficient in calcium and phosphorus
(Taylor & Francis Ltd, 2015)1. Two experiments were designed to determine the effect of dietary boron (B) in broiler chickens. In Experiment 1, a 2x4 factorial arrangement of treatments was used to investigate the effect of dietary calcium (Ca) and ... -
Single dose varenicline may trigger epileptic activity
(Springer-Verlag Italia Srl, 2014)Varenicline is a new drug for smoking cessation, and its effect on epilepsy is not clear. The aim of this study was to investigate whether different doses of varenicline cause epileptic activity. Forty rats were randomly ... -
Histopathological changes in rat pancreas and skeletal muscle associated with high fat diet induced insulin resistance
(Taylor & Francis Ltd, 2015)The effects of a high fat diet on the development of diabetes mellitus, insulin resistance and secretion have been widely investigated. We investigated the effects of a high fat diet on the pancreas and skeletal muscle of ... -
Prevention of ovarian hyperstimulation syndrome in a rat model: comparison of the efficacy of tocilizumab with that of ranibizumab, cabergoline, and a gonadotropin-releasing Hormone antagonist
(Taylor & Francıs Ltd, 2015)The aim of the study is to investigate the effects of the interleukin-6 (IL-6) blocker tocilizumab in a hyperstimulated rat model and compare it with ranibizumab, a gonadotropin-releasing hormone antagonist (GnRHA), and ... -
Boric acid reduces axonal and myelin damage in experimental sciatic nerve injury
(Medknow Publications & Media Pvt Ltd, 2016)The aim of this study was to investigate the effects of boric acid in experimental acute sciatic nerve injury. Twenty-eight adult male rats were randomly divided into four equal groups (n = 7): control (C), boric acid (BA), ... -
Genetic variations in tumor necrosis factor alpha, interleukin-10 genes, and migraine susceptibility
(Wiley-Blackwell, 2011)Objectives. Migraine is a very common headache disorder and pathogenesis of the disease is still largely unknown. Cytokine genes have been implicated in migraine susceptibility. The present study was designed to explore ... -
Protective effects of CAPE on liver injury induced by CCL4: An electron microscopy study
(Informa Healthcare, 2011)This study was designed to investigate the protective effects of caffeic acid phenethyl ester on carbon tetrachloride-induced liver damage in rats. Twenty-four male Wistar rats were divided in three groups. Group I was ... -
Apoptosis rate in malignant mammary tumours in bitches
(Ecole Nationale Veterinaire Toulouse, 2011)As the equilibrium between cell division and cell death (apoptosis) determines the growth of a tumour, the aim of the study was to evaluate the apoptosis frequency in dog mammary tumours both by the TdT-mediated dUTP-biotin ... -
Evaluation of biochemical findings in mice exposed to thiamphenicol treatment
(Academic Journals, 2011)The aim of the study was to investigate the acute and subacute dose and the dose regime of thiamphenicol-induced changes in serum biochemical parameters in mice. Thiamphenicol was given to the trial groups at a dosage of ... -
The effect of lavender oil on serum testosterone levels and epididymal sperm characteristics of formaldehyde treated male rats
(Verduci Publisher, 2011)Background and Objectivies: In this study, the harmful effects of formaldehyde (FA) on serum testosterone levels and epididymal sperm characteristics were investigated. In addition, possible protective effect of lavender ... -
Hepatotoxic activity of toluene inhalation and protective role of melatonin
(Sage Publications Inc, 2011)This study was designed to investigate the harmful effects of toluene inhalation in the liver of rats and possible protective effects of melatonin on these detrimental effects. For this purpose, 21 adult male Wistar-albino ... -
Effects of lemon essential oil aroma on the learning behaviors of rats
(Riyadh Armed Forces Hospital, 2010)Essential oils (EO) are volatile odors obtained from various plants. Their usage dates from ancient India and Egypt, and they have been used for more than 5 thousand years. The EO can be produced by distillation, expression, ... -
Effects of testosterone on orchiectomy-induced oxidative damage in the rat hippocampus
(Elsevier Science Bv, 2010)The aim of this study was to investigate the morphological changes of the hippocampus after orchiectomy and the protective effects of testosterone on these changes. Animals were divided into 3 groups. The rats in group ... -
Exercise and DHA prevent the negative effects of hypoxia on EEG and nerve conduction velocity
(Mary Ann Liebert, 2013)Erken, Haydar Ali, Gulten Erken, Ridvan Colak, Osman Genc. Exercise and DHA prevent the negative effects of hypoxia on EEG and nerve conduction velocity. High Alt Med Biol 14:360-366, 2013.It is known that hypoxia has a ... -
An investigation of participating to continuous medical education programs of medical staff at a state hospital
(Duzce University Medical School, 2015)Aim: This study was planned to determine the frequency, funding and effectiveness of continuous medical education programs which the medical staff at a state hospital attended. Method: This descriptive research was performed ... -
Evaluation of the effects of dexketoprofen trometamol on knee joint: An in vivo & in vitro study
(Indian Council Medical RES, 2013)Background & objectives: Intra-articular (ia) injections of local anaesthetics and non-steroidal anti-inflammatory drugs (NSAID's) are simple and efficient to ensure post-operative analgesia but some of these have toxic ... -
Selenium protects retinal cells from cisplatin-induced alterations in carbohydrate residues
(Galenos Yayincilik, 2016)Background: Investigate alterations in the expression and localization of carbohydrate units in rat retinal cells exposed to cisplatin toxicity. Aims: The aim of the study was to evaluate putative protective effects of ...