Güncel Gönderiler: Temel Tıp Bilimleri-Makale Koleksiyonu
Toplam kayıt 280, listelenen: 141-160
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Volume estimation of brain ventricles using Cavalieri's principle and Atlas-based methods in Alzheimer disease: Consistency between methods
(Elsevier Sci Ltd, 2020)Automatic estimations of brain ventricles are needed to assess disease progression in neurodegenerative disorders such as Alzheimer Disease (AD). The objectives of this study are to evaluate the diagnostic performances of ... -
Molecular genetic analysis of Turkish Gaucher's disease patients reveals three novel variants in Glucocerebrosidase (GBA) gene
(Elsevier, 2020)Gaucher's disease (GD) is the most prevalent lysosomal storage disorder caused by the deficiency of beta-gluco-sylceramidase enzyme (EC 3.2.1.45) due to mutations in the GBA gene. To date, more than 400 GBA mutations have ... -
Immunohistochemical evidence for glutamatergic regulation of nesfatin-1 neurons in the rat hypothalamus
(MDPI, 2020)Nesfatin-1, identified as an anorexigenic peptide, regulates the energy metabolism by suppressing food intake. The majority of nesfatin-1-synthesizing neurons are concentrated in various hypothalamic nuclei, especially in ... -
Evaluation of mycobacterium tuberculosis culture and drug susceptibility test results and the distribution of nontuberculosis mycobacteria from the clinical specimens
(Ankara Microbiology Soc, 2020)Tuberculosis (TB) continues to pose a significant public health problem worldwide. For mycobacteriology laboratories, it is important to be able to diagnose active cases and to make a differential diagnosis of non-tuberculous ... -
The relationship between vitamin D gene polymorphisms and the diagnosis of prostate cancer in patients with high prostate-specific antigen value
(Galenos Yayıncılık, 2020)Objective: To investigate the effects of vitamin D levels and vitamin D receptor (VDR) BsmI, FokI, TaqI, and ApaI gene polymorphisms on prostate cancer (PCa) diagnosis in Turkish men with high prostate-specific antigen ... -
Frequently isolated slow growing nontuberculous mycobacteria from pulmonary samples and evaluation of drug susceptibility testing results in a referral hospital in Turkey
(Ankara Microbiology Soc, 2019)Most of the nontuberculous mycobacteria (NTM) are opportunistic pathogenic microorganisms and free-living in nature. NTM can cause a wide range of infections. However, pulmonary NTM disease is the most frequent clinical ... -
Effects of exercise training on anxiety in diabetic rats
(Elsevier, 2019)Diabetes mellitus (DM) is a common health problem, which manifests itself with chronic hyperglycemia and impaired insulin action. The prevalence of anxiety disorders tends to be high in the diabetic population. Exercise ... -
Brain asymmetry in directing attention during dichotic listening test: An fNIRS study
(Routledge Journals, 2019)In a classical dichotic listening paradigm, besides auditory brain asymmetry, cognitive functions such as attention and conflict resolution play a major role. The aim of this study is to reveal the possible haemodynamic ... -
Impairment of lipophagy by PNPLA1 mutations causes lipid droplet accumulation in primary fibroblasts of autosomal recessive congenital ichthyosis patients
(Elsevier Ireland LTD, 2019)Background: Autosomal Recessive Congenital Ichthyosis (ARCI) is a group of epidermal keratinization disorders. One of the disease-associated proteins, patatin-like phospholipase domain-containing protein-1 (PNPLA1), plays ... -
The anatomy of the sigmoid-transverse junction according to the tentorial angle
(Lippincott Williams & Wilkins, 2019)Dural sinuses have critical importance during intracranial approaches. Detailed anatomical knowledge of the dural sinuses is crucial for surgeons to reduce unexpected venous bleeding. The aim of this study was to investigate ... -
The impact of type II diabetes on tongue dysplasia and P16-related aging process: An experimental study
(Hindawi LTD, 2019)Objective. To evaluate the effect of streptozotocin-induced experimental diabetes mellitus on p16, p53, Ki67, and Bcl2 expressions and histopathological changes in the tongue of the rats. Material and Methods. Twenty-two ... -
Duloxetine alleviates high light-induced anxiety-related behaviors in wistar rats
(Pharmacotherapy Group, 2019)Purpose: To investigate the effect of subchronic duloxetine treatment on high light-induced anxiety-related behaviors in Wistar rats. Methods: Adult male Wistar rats (n = 30) were randomly assigned to three groups of ... -
Orexin and adiponectin in high fat diet-induced insulin resistance
(Taylor & Francis LTD, 2019)Orexin A (OXA) is a hypothalamic neuropeptide with both central and peripheral activities on insulin signaling and energy balance. Adiponectin is an adipocytokine which regulates metabolisms of lipid and glucose via its ... -
Ozone partially decreases axonal and myelin damage in an experimental sciatic nerve ınjury model
(Taylor & Francis INC, 2019)Aim: To investigate the effects of ozone in experimental acute sciatic nerve injury. Material and Methods: Twenty-eight male rats were divided into four groups (n = 7): control (C), ozone (O), injury (SNI), and treatment ... -
Changes in pro-inflammatory cytokines and antimicrobial proteins in elderly women with iron deficiency anemia
(Professional Medical Publications, 2019)Objective: Iron Deficiency Anemia (IDA) is common nutritional deficiency particularly in women and also common during the older age. Aging increases plasma levels of inflammatory mediators such as pro-inflammatory cytokines ... -
Plasma neuropeptide-s levels in populations diagnosed with generalized anxiety disorder: a controlled study
(Aves, Buyukdere Cad 105-9, 2019)Introduction: Neuropeptide S (NPS) is a novel neuropeptide reported to be involved in fear- and stress-related conditions and their corresponding neuroendocrine processes. The aim of this study was to compare the plasma ... -
Redefining the morphometry of subclavian vessels for clavicle fracture treatments
(Springer France, 2019)PurposeClavicle fractures are common injuries in adults and children. Although neurovascular damage is rarely seen, acute subclavian artery pseudoaneurysms and injuries to subclavian vessels were reported for closed fractures ... -
Experimental acute myocardial infarction in rats: HIF-1α, caspase-3, erythropoietin and erythropoietin receptor expression and the cardioprotective effects of two different erythropoietin doses
(Elsevier Bmgh, 2013)The cardioprotective effects of two different doses of erythropoietin administration were analyzed in rats with experimental myocardial infarction. None, saline, standard-dose (5000 U kg(-1)) and high-dose (10,000 U kg(-1)) ... -
Blood pressure measurement in freely moving rats by the tail cuff method
(Informa Healthcare, 2013)Inconsistency in consecutive blood pressure values is one of the most frequently observed problems in tail cuff method. The aim of this study was to measure blood pressure using the tail cuff method in rats without heating, ... -
Increased red blood cell deformability and decreased aggregation as potential adaptive mechanisms in the slow coronary flow phenomenon
(Lippincott Williams & Wilkins, 2013)Objective At present, the precise pathophysiology of the slow coronary flow phenomenon (SCFP) is still unknown and there is no consensus as to how it should be treated. The rheological factors affect the clinical course ...
