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dc.contributor.authorErken, Haydar Ali
dc.contributor.authorErken, Gülten
dc.contributor.authorYay, Arzu
dc.contributor.authorGöktepe, Özge
dc.date.accessioned2022-04-01T06:21:36Z
dc.date.available2022-04-01T06:21:36Z
dc.date.issued2021en_US
dc.identifier.issn0894-1939 -1521-0553
dc.identifier.urihttps://doi.org/10.1080/08941939.2021.2022251
dc.identifier.urihttps://hdl.handle.net/20.500.12462/12163
dc.descriptionErken, Haydar Ali (Balikesir Author)en_US
dc.description.abstractBackground: Although in vitro methods have disadvantages, they are still commonly used to measure nerve conduction velocity (NCV) in experimental studies. Therefore, this study was designed to demonstrate the effect of the surgical procedures required for in vitro methods on nerve fibers and the effect of in vivo and in vitro methods on the results of electrophysiological measurements. Methods: Rats were assigned to the in vivo (control-1, injury-1, and diabetic-1) and in vitro (control-2, injury-2, and diabetic-2) groups. The NCV and compound action potential amplitudes were measured, and the nerve fibers were histologically examined. Results: Damaged axons and myelin sheaths were observed in the control-2 group. The electrophysiological values of the in vitro groups were lower than those of the in vivo groups. Furthermore, these values were lower for the diabetic and injury groups than for the control groups. Conclusions: This study showed that the surgical procedures required for the in vitro method reduced the measured values. Owing to the previous and current disadvantages of the in vitro method, the in vivo method was more sensitive for the NCV measurement. Moreover, measurements can be performed using the current in vivo method for small nerve fibers.en_US
dc.language.isoengen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.isversionof10.1080/08941939.2021.2022251en_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectInjuryen_US
dc.subjectIn Vitroen_US
dc.subjectIn Vivoen_US
dc.subjectNerve Conduction Velocityen_US
dc.subjectSurgical Proceduresen_US
dc.titleSurgical procedures required for measurement reduce nerve conduction velocity: An in vivo and in vitro comparative studyen_US
dc.typearticleen_US
dc.relation.journalJournal of Investigative Surgeryen_US
dc.contributor.departmentTıp Fakültesien_US
dc.identifier.volumeEarly Access DEC 2021en_US
dc.identifier.startpage1en_US
dc.identifier.endpage7en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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