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dc.contributor.authorYılmaz, Anıl
dc.contributor.authorÇağlar, Pınar
dc.contributor.authorDirmenci, Tuncay
dc.contributor.authorGören, Nezhun
dc.contributor.authorTopçu, Gülaçtı
dc.date.accessioned2019-12-11T08:32:44Z
dc.date.available2019-12-11T08:32:44Z
dc.date.issued2012en_US
dc.identifier.issn1934-578X
dc.identifier.urihttps://hdl.handle.net/20.500.12462/10272
dc.descriptionDirmenci, Tuncay (Balikesir Author)en_US
dc.description.abstractFrom the dichloromethane extract of Nepeta sorgerae, the isolation and structure elucidation are now reported of a new isopimarane diterpenoid, named sorgerolone, and two known triterpenoids, oleanolic acid and ursolic acid. Antioxidant activity of the extracts and the isolated terpenoids was determined by the DPPH free radical scavenging and lipid peroxidation inhibition (beta-carotene bleaching) methods. Anticholinesterase activity of the extracts and isolates was investigated by Ellman's method against AChE and BChE enzymes. Although the antioxidant activity results were low, the AChE enzyme inhibition of the extracts and terpenoids was very promising.en_US
dc.description.sponsorshipIstanbul Technical University - 34028en_US
dc.language.isoengen_US
dc.publisherNatural Products Incen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNepeta Sorgeraeen_US
dc.subjectIsopimarane Diterpeneen_US
dc.subjectTriterpenoidsen_US
dc.subjectAntioxidant Activityen_US
dc.subjectAnticholinesterase Activityen_US
dc.titleA novel isopimarane diterpenoid with acetylcholinesterase inhibitory activity from Nepeta sorgerae, an endemic species to the Nemrut Mountainen_US
dc.typearticleen_US
dc.relation.journalNatural Product Communicationsen_US
dc.contributor.departmentNecatibey Eğitim Fakültesien_US
dc.contributor.authorID0000-0002-7946-6545en_US
dc.contributor.authorID0000-0003-1170-4671en_US
dc.contributor.authorID0000-0002-0704-6306en_US
dc.contributor.authorID0000-0003-3038-6904en_US
dc.identifier.volume7en_US
dc.identifier.issue6en_US
dc.identifier.startpage693en_US
dc.identifier.endpage696en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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