Yazar "Zorlu, Gökhan" için listeleme
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Effect of metaclopramide on urinary bladder smooth muscle contraction-relaxation mechanism
Ercan, Zübeyde; Zorlu, Gökhan; Bulmuş, Özgür; Serhatlıoğlu, İhsan; Yaşar, Abdullah; Kaçar, Emine (2022)Objectives: Metoclopramide, a dopamine receptor antagonist, a benzamide, is a commonly used antiemetic drug in many diseases with nausea and vomiting. The aim of this study is to examine the effects of metoclopramide, which ... -
Investigation the effect of ramelteon on urinary bladder smoth muscle contraction-relaxation mechanism
Serhatlıoğlu, İhsan; Hekim, Münevver Gizem; Zorlu, Gökhan; Bulmuş, Özgür; Yaşar, Abdullah; Kaçar, Emine (İnönü Üniversitesi Tıp Fakültesi, 2022)Aim: A melatonin receptor agonist ramelteon is a drug that is also used in urinary tract infections. Melatonin is known to have an effect on smooth muscle contraction. In this study, we aimed to question whether ramelteon ... -
Modulation of melatonin receptors regulates reproductive physiology: The impact of agomelatine on the estrus cycle, gestation, offspring, and uterine contractions in rats
Kaçar, Emine; Tan, Fatih; Şahintürk, Serdar; Zorlu, Gökhan; Serhatlıoğlu, İhsan; Bulmuş, Özgür; Ercan, Zübeyde; Keleştimur, Haluk (Acad Sciences Czech Republic, 2023)Agomelatine is a pharmaceutical compound that functions as an agonist for melatonin receptors, with a particular affinity for the MT1 and MT2 receptor subtypes. Its mode of action is integral to the regulation of diverse ... -
Treadmill exercise has healing effects on obesity-induced sexual behavior disorder through kisspeptin and kiss1R expression in male rats
Kaçar, Emine; Bulmuş, Özgür; Ercan, Zübeyde; Kavuran, İlay Buran; Zorlu, Gökhan; Tan, Fatih; Serhatlıoğlu, İhsan; Keleştimur, Haluk (C M B Assoc, 2023)The basic objective of this study was to examine the possible effects of treadmill exercise on obesity-related sexual behavior disorder in obese male rats and the role of kisspeptin in this effect. The rats were separated ... -
Treadmill exercise improves behavioral and neurobiological alterations in restraint-stressed rats
Ercan, Zübeyde; Bulmuş, Özgür; Kaçar, Emine; Serhatlıoğlu, İhsan; Zorlu, Gökhan; Kelestimur, Haluk (Springer Nature, 2023)Stress is a state that is known to impact an organism's physiological and psychological balance as well as the morphology and functionality of certain brain areas. In the present work, chronic restraint stress (CRS) model ... -
TRPM2 may be involved in high fructose corn syrup-induced anxiety-like behavior in adult male rats
Serhatlıoğlu, İhsan; Zorlu, Gökhan; Yardımcı, Ahmet; Ertuğrul, Nazife Ülker; Ercan, Zübeyde; Tan, Fatih; Bulmuş, Özgür; Bulmuş, Funda Gülcü (C M B Assoc, 2023)Excessive high fructose corn syrup (HFCS) consumption is known to cause oxidative stress, which induces transient receptor potential melastatin type 2 (TRPM2) channel gating. Oxidative stress-induced TRPM2 gating is suggested ...
