Yazar "Utkan, Tijen" için listeleme
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Chronic etanercept treatment exerts antidepressant-like effect in cafeteria diet-fed rats
Utkan, Tijen; Demirtaş, Tuğçe; Aksöz, Elif; Arkan, Sertan (Elsevier Science BV, 2015)Purpose of the study: An increasing number of studies have revealed that obesity is associated with depression. Recent studies also have reported that obesity is not only as a metabolic disorder but also as an inflammatory ... -
Effect of etanercept, a tnf-alpha inhibitor, on depressive-like behavior in cafeteria diet-fed rats
Şahin, Tuğçe Demirtaş; Utkan, Tijen; Aksöz, Elif; Karson, Ayse (Elsevier Science BV, 2015)Background: Obesity has been shown to be associated with depression. Recent studies have reported that obesity is not only as a metabolic disorder but also as an inflammatory disease. In this study we explored the effect ... -
The effects of propolis extract on age-associated cognitive deficits in rats
Göçmez, Semil Selcen; Çelebi, G.; Demirtaş-Şahin, T.; Aksöz, Elif; Utkan, Tijen (Elsevier, 2019)Background: Propolis is widely used as alternative medicinal product due to their antimicrobial, antiinflammatory and antioxidant properties. Previous studies have shown that propolis has a neuroprotective effect and ... -
Etanercept treatment prevents emotional memory deficits of cafeteria diet-fed rats
Şahin, Tuğçe Demirtaş; Utkan, Tijen; Aksöz, Elif; Karson, Ayşe (Elsevier Science BV, 2015)Background: Obesity has been shown to degrade cognitive functions, including memory. Recent evidence suggests that obesity also results in inflammation in the brain. In this study we investigated the effect of etanercept ... -
The protective effect of metformin in scopolamine-induced learning and memory impairment in rats
Aksöz, Elif; Göçmez, Semil Selcen; Şahin, Tuğçe Demirtaş; Akşit, Dilek; Akşit, Hasan; Utkan, Tijen (Polish Acad Sciences Inst Pharmacology, 2019)Background: Alzheimer's disease (AD) is the most common neurodegenerative disease in the world. One of the most commonly prescribed oral antidiabetic drug, metformin, has been shown to have beneficial effects on restoring ... -
Protective effects of an extract of propolis in scopolamine-induced cognitive impairment in rats
Utkan, Tijen; Demirtaş Şahin, Tuğçe; Göçmez, Semil; Aksöz, Elif; Gacar, Nejat (Elsevier Science BV, 2015)Purpose: Propolis is a natural substance collected by honeybees from buds and exudates of certain trees which has antioxidant, antibacterial, antiviral and anti-inflammatory and neuroprotective effect in neurodegenerative ... -
Protective effects of metformin in scopolamine-induced cognitive impairment in rats
Aksöz, Elif; Göçmez, Semil Sevcen; Demirtaş, Tuğçe; Utkan, Tijen (Elsevier Science BV, 2015)Purpose:Epidemiological, clinical and experimental data supporta link between type 2 diabetes mellitus and Alzheimer’s disease(AD). AD is a progressive neurodegenerative disorder of the brainthat is characterized by ...