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Endotrophin as a novel marker in PCOS and its relation with other adipokines and metabolic parameters: a pilot study
Güney, Gürhan; Taşkın, Mine İslimye; Baykan, Özgür; Tezcan, Selin Gül; Sarıkaya, Serkan; Kaya, Cihan; Tolu, Ezgi (Sage Publications Ltd, 2021)Background: Polycystic ovary syndrome is known to be the most common hormonal disorder in women of reproductive age. Current evidence shows that regulatory proteins secreted from the adipose tissue called adipokines may ... -
Neutrophil gelatinase-associated lipocalin serum level: A potential noninvasive biomarker of endometriosis?
Güney, Gürhan; Taşkın, Mine İslimye; Lagana, Antonio Simone; Tolu, Ezgi; Aslan, Figen; Hişmioğulları, Adnan Adil; Kaya, Cihan (Lippincott Williams & Wilkins, 2023)Neutrophil gelatinase-associated lipocalin (NGAL, also known as lipocalin-2) is an acute-phase protein expressed in many tissues and plays a role in cell proliferation, regulation, and epithelial-mesenchymal transformation. ... -
The role of ERK-1 and ERK-2 gene polymorphisms in PCOS pathogenesis
Güney, Gürhan; Taşkın, Mine İslimye; Şener, Nazlı; Tolu, Ezgi; Dodurga, Yavuz; Elmas, Levent; Çetin, Orkun; Sarıgül, Cengiz (BMC, 2022)Background: Ovulation is regulated by extracellular signal-regulated kinase-1 (ERK-1) and ERK-2 signaling mechanisms, and ERK-1/2 kinases modulates the function of most of the LH-regulated genes. Defective ERK kinase ...
