Yazar "Sekkin, Selim" için listeleme
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Comparative pharmacokinetics and bioavailability of albendazole sulfoxide in sheep and goats, and dose-dependent plasma disposition in goats
Akşit, Dilek; Yalınkılıç, Hande Sultan; Sekkin, Selim; Boyacıoğlu, Murat; Çırak, Veli Yilgor; Ayaz, Erol; Gökbulut, Cengiz (BMC, 2015)Background: The aims of this study were to compare the pharmacokinetics of albendazole sulfoxide (ABZ-SO, ricobendazole) in goats and sheep at a dose of 5 mg/kg bodyweight (BW), after intravenous (IV) and subcutaneous (SC) ... -
In vivo exposure of Albendazole sulphoxide by Haemonchus contortus and correlation between plasma and target tissue or gastrointestinal content dispositions in goats
Gökbulut, Cengiz; Çırak, Veli Y.; Aypak, Suleyman; Avcı, Hamdi; Sekkin, Selim; Yalınkılınç, Hande S.; Boğa, Buket; Ayaz, Erol (Wiley, 2021)Sheep and goats are sharing different helminth parasites including Haemonchus contortus. Control of these helminths is based mainly on the use of anthelmintics. However, in goats, the application of anthelmintics is often ... -
Protective and antigenotoxic effects of silymarin and curcumin in experimental cyclophosphamide ıntoxication in rats
Avcı, Hamdi; Sekkin, Selim; Boyacıoğlu, Murat; Akşit, Hasan; Tunca, Recai; Epikmen, Erkmen Tuğrul; Birincioğlu, Sümbül Serap (Kafkas Üniv, 2016)The aim of this study was to investigate the protective effects of silymarin (SLY) and curcumin (CUR), which have strong antioxidant properties, against the toxic effects of high dose of cyclophosphamide (CP) on the liver ... -
Protective effects of silymarin and curcumin on cyclophosphamide-induced cardiotoxicity
Avcı, Hamdi; Epikmen, Erkmen Tuğrul; İpek, Emrah; Tunca, Recai; Birincioğlu, Sümbül Serap; Akşit, Hasan; Sekkin, Selim; Akkoç, Ayşe Nur (Elsevier Gmbh, 2017)"Introduction: Cyclophosphamide (CP) is a potent anticancer agent; its clinical use is limited due to its marked cardiotoxicity. Aim: The present study was aimed at evaluating the cardioprotective effects of silymarin ...
