Yazar "Seçme, Mücahit" için listeleme
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Erianin as a promising novel agent in the treatment of neuroblastoma: The anti-cancer effects and underlying molecular mechanisms
Koçoğlu, Sema Serter; Seçme, Mücahit; Sunay, Fatma Bahar (Bentham Science Publishers, 2023)Background: Erianin is an active dibenzyl compound isolated from Dendrobium officinale and Dendrobium chrysotoxum and there are very few studies on molecular mechanisms and drug targets of erianin. In addition, there is ... -
Erianin, a promising agent in the treatment of glioblastoma multiforme triggers apoptosis in U373 and A172 glioblastoma cells
Koçoğlu, Sema Serter; Seçme, Mücahit; Elmas, Levent (Inst Bioloska Istrazivanja Sinisa Stankovic, 2022)Glioblastoma is an aggressive, common and deadly primary intracranial brain tumor in adults. The antitumor activity of erianin, a dibenzyl compound found in Dendrobium chrysotoxum Lindl. extract, has not been previously ... -
Erianinin HT29 kolorektal kanser hücrelerinin proliferasyonu ve koloni oluşumu üzerine etkilerinin araştırılması
Koçoğlu, Sema Serter; Elmas, Levent; Seçme, Mücahit (Seyhan Miğal, 2021)Kolorektal kanser, dünyada kanser ilişkili ölümlerin en yaygın dördüncü sebebidir. Erianin antioksidan ve anti-tümör etkilere sahip Dendrobium ekstraktından elde edilen yeni bir dibenzil bileşiğidir. Bu çalışmada, erianinin ... -
Investigation of the anticancer mechanism of monensin via apoptosis-related factors in SH-SY5Y neuroblastoma cells
Koçoğlu, Sema Serter; Oy, Ceren; Seçme, Mücahit; Sunay, Fatma Bahar (Wiley, 2023)Monensin is an ionophore antibiotic that inhibits the growth of cancer cells. The aim of this study was to investigate the apoptosis-mediated anticarcinogenic effects of monensin in SH-SY5Y neuroblastoma cells. The effects ... -
Investigation of the TLR4 and IRF3 signaling pathway-mediated effects of monensin in colorectal cancer cells
Seçme, Mücahit; Koçoğlu, Sema Serter (Springer, 2023)Monensin is an ionophore antibiotic isolated from Streptomyces cinnamonensis with very strong antibacterial and antiparasitic effects. Although monensin is known to exhibit anticancer activity in different cancer types, ... -
Monensin, an antibiotic isolated from streptomyces cinnamonensis, regulates human neuroblastoma cell proliferation via the PI3K/AKT signaling pathway and acts synergistically with rapamycin
Koçoğlu, Sema Serter; Seçme, Mücahit; Oy, Ceren; Korkusuz, Gözde; Elmas, Levent (MDPI, 2023)Neuroblastoma is the most common extracranial childhood tumor and accounts for approximately 15% of pediatric cancer-related deaths. Further studies are needed to identify potential therapeutic targets for neuroblastoma. ... -
Monensinin glioblastoma multiformede kaspaz-10 aracılı apoptoz üzerine etkileri
Koçoğlu, Sema Serter; Seçme, Mücahit (Seyhan Miğal, 2021)Glioblastoma multiforme (GBM), en kötü huylu primer merkezi sinir sistemi tümörüdür. Şu anda, GBM için iyileştirici tedavi seçenekleri yoktur ve 5 yıllık hayatta kalma oranı %5’den daha azdır. Monensin, ‘’Streptomyces ...
