Yazar "Scozzafava, Andrea" için listeleme
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Anion inhibition studies of the α-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae
Vullo, Daniela; Işık, Semra; Del Prete, Sonia; De Luca, Viviana; Carginale, Vincenzo; Scozzafava, Andrea; Supuran, Claudiu; Capasso, Clemente (Pergamon - Elsevier Ltd, 2013)An alpha-carbonic anhydrase (CA, EC 4.2.1.1) has been recently cloned and characterized in the human pathogenic bacterium Vibrio cholerae, denominated VchCA (Del Prete et al. J. Med. Chem. 2012, 55, 10742). This enzyme ... -
Carbonic anhydrase activators: Activation of the β-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids
Işık, Semra; Köçkar, Feray; Aydın, Meltem; Arslan, Oktay; Güler, Özen Özensoy; Innocenti, Alessio; Scozzafava, Andrea; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2009)The protein encoded by the Nce103 gene of Saccharomyces cerevisiae, a beta-carbonic anhydrase (CA, EC 4.2.1.1) designated as scCA, was investigated for its activation with amines and amino acids. scCA was poorly activated ... -
Carbonic anhydrase inhibitors. Inhibition of red blood cell ostrich (Struthio camelus) carbonic anhydrase with a series of aromatic and heterocyclic sulfonamides
Özensoy, Özen; Arslan, Oktay; Işık, Semra; Arslan, Mikail; Scozzafava, Andrea; Supuran, Claudiu T. (Taylor & Francis Ltd, 2005)The purification of red blood cell carbonic anhydrase (CA, EC 4.2. 1. 1) from ostrich (scCA) blood is reported, as well as an inhibition study of this enzyme with a series of aromatic and heterocylic sulfonamides. The ... -
Carbonic anhydrase inhibitors: Inhibition of the tumor-associated isozymes IX and XII with a library of aromatic and heteroaromatic sulfonamides
Özensoy, Özen; Puccetti, Luca; Fasolis, Giuseppe; Arslan, Oktay; Scozzafava, Andrea; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2005)The inhibition of the two transmembrane, tumor-associated isozymes of carbonic anhydrase (CA, EC 4.2.1.1) of human origin, hCA IX and XII, with a library of aromatic and heteroaromatic sulfonamides has been investigated. ... -
Carbonic anhydrase inhibitors: Inhibition of the β-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates
Işık, Semra; Köçkar, Feray; Aydın, Meltem; Arslan, Oktay; Güler, Özen Özensoy; Innocenti, Alessio; Scozzafava, Andrea; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2009)The protein encoded by the Nce103 gene of Saccharomyces cerevisiae, a beta-carbonic anhydrase ( CA, EC 4.2.1.1) designated as scCA, has been cloned, purified, characterized kinetically and investigated for its inhibition ... -
DNA cloning, characterization, and inhibition studies of an alpha-carbonic anhydrase from the pathogenic bacterium vibrio cholerae
Del Prete, Sonia; Işık, Semra; Vullo, Daniela; De Luca, Viviana; Carginale, Vincenzo; Scozzafava, Andrea; Supuran, Claudiu T.; Capasso, Clemente (Amer Chemical Soc, 2012)We have cloned, purified, and characterized an alpha-carbonic anhydrase (CA, EC 4.2.1.1) from the human pathogenic bacterium Vibrio cholerae, VchCA. The new enzyme has significant catalytic activity, and an inhibition study ...
