Yazar "Maresca, Alfonso" için listeleme
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Mutation of active site residues Asn67 to Ile, Gln92 to Val and Leu204 to Ser in human carbonic anhydrase ii: influences on the catalytic activity and affinity for inhibitors
Türkoğlu, Sümeyye; Maresca, Alfonso; Alper, Meltem; Köçkar, Feray; Işık, Semra; Sinan, Selma; Özensoy, Özen; Arslan, Oktay (Pergamon-Elsevier Science Ltd, 2012)Site-directed mutagenesis has been used to change three amino acid residues involved in the binding of inhibitors (Asn67Ile; Gln92Val and Leu204Ser) within the active site of human carbonic anhydrase (CA, EC 4.2.1.1) II ... -
Mutation of phe91 to asn in human carbonic anhydrase ı unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors
Köçkar, Feray; Maresca, Alfonso; Işık, Semra; Türkoğlu, Sümeyye; Sinan, Selma; Arslan, Oktay; Güler, Özen Özensoy; Turan, Yusuf (Pergamon-Elsevier Science Ltd, 2010)Site-directed mutagenesis has been used to change one amino acid residue considered non essential (Phe91Asn) to catalysis in carbonic anhydrase (CA, EC 4.2.1.1) isozyme I (hCA I), but which is near the substrate binding ...
