Yazar "Kaçar, Emine" için listeleme
-
Effect of agomelatine on intestinal smooth muscle contractility in rats
Kaçar, Emine; Şahintürk, Serdar; Yardımcı, Ahmet; Ülker, Nazife; Tan, Fatih; Bulmuş, Özgür; Ercan, Zübeyde (İnönü Üniversitesi Tıp Fakültesi, 2022)Aim: The purpose of the present study was to investigate in vitro the effect of agomelatine, an analog of melatonin, on potassium chloride-stimulated contractions (KCl) in duodenum, jejunum, ileum, and colon in ... -
Effect of metaclopramide on urinary bladder smooth muscle contraction-relaxation mechanism
Ercan, Zübeyde; Zorlu, Gökhan; Bulmuş, Özgür; Serhatlıoğlu, İhsan; Yaşar, Abdullah; Kaçar, Emine (2022)Objectives: Metoclopramide, a dopamine receptor antagonist, a benzamide, is a commonly used antiemetic drug in many diseases with nausea and vomiting. The aim of this study is to examine the effects of metoclopramide, which ... -
Effects of treadmill exercise on sexual behavior and reproductive parameters in chronically stressed-male rats
Kelestimur, Haluk; Bulmuş, Özgür; Serhatlıoğlu, İhsan; Ercan, Zübeyde; Kaya, Şeyma Özer; Yardımcı, Ahmet; Ülker, Nazife; Kaçar, Emine; Canpolat, Sinan (Acad Sciences Czech Republic, 2021)Exposure to chronic stress stimulates the hypothalamic-pituitary adrenal (HPA) axis and then simultaneously inhibits hypothalamic-pituitary-gonadal axis (HPG) axis activity. The inhibition formed by the HPA axis is the ... -
Investigation the effect of ramelteon on urinary bladder smoth muscle contraction-relaxation mechanism
Serhatlıoğlu, İhsan; Hekim, Münevver Gizem; Zorlu, Gökhan; Bulmuş, Özgür; Yaşar, Abdullah; Kaçar, Emine (İnönü Üniversitesi Tıp Fakültesi, 2022)Aim: A melatonin receptor agonist ramelteon is a drug that is also used in urinary tract infections. Melatonin is known to have an effect on smooth muscle contraction. In this study, we aimed to question whether ramelteon ... -
Modulation of melatonin receptors regulates reproductive physiology: The impact of agomelatine on the estrus cycle, gestation, offspring, and uterine contractions in rats
Kaçar, Emine; Tan, Fatih; Şahintürk, Serdar; Zorlu, Gökhan; Serhatlıoğlu, İhsan; Bulmuş, Özgür; Ercan, Zübeyde; Keleştimur, Haluk (Acad Sciences Czech Republic, 2023)Agomelatine is a pharmaceutical compound that functions as an agonist for melatonin receptors, with a particular affinity for the MT1 and MT2 receptor subtypes. Its mode of action is integral to the regulation of diverse ... -
Relaxing effects of paracetamol on uterine spontaneous contraction in rats in vitro
Kaçar, Emine; Bulmuş, Özgür; Ercan, Zübeyde; Zorlu, Gokhan; Yaşar, Abdullah; Serhatlıoğlu, İhsan (2022)Aim: Paracetamol is a commonly used drug in acute and chronic pain. It is known that paracetamol, which is a pain reliever and antipyretic drug, is safe to use during pregnancy. The aim of this study was to investigate the ... -
Treadmill exercise has healing effects on obesity-induced sexual behavior disorder through kisspeptin and kiss1R expression in male rats
Kaçar, Emine; Bulmuş, Özgür; Ercan, Zübeyde; Kavuran, İlay Buran; Zorlu, Gökhan; Tan, Fatih; Serhatlıoğlu, İhsan; Keleştimur, Haluk (C M B Assoc, 2023)The basic objective of this study was to examine the possible effects of treadmill exercise on obesity-related sexual behavior disorder in obese male rats and the role of kisspeptin in this effect. The rats were separated ... -
Treadmill exercise improves behavioral and neurobiological alterations in restraint-stressed rats
Ercan, Zübeyde; Bulmuş, Özgür; Kaçar, Emine; Serhatlıoğlu, İhsan; Zorlu, Gökhan; Kelestimur, Haluk (Springer Nature, 2023)Stress is a state that is known to impact an organism's physiological and psychological balance as well as the morphology and functionality of certain brain areas. In the present work, chronic restraint stress (CRS) model ... -
Treadmill exercise training improves the high-fat diet-induced behavioral changes in the male rats
Bulmuş, Özgür; Ercan, Zübeyde; Kaçar, Emine; Serhatlıoğlu, İhsan; Yaşar, Abdullah; Kelestimur, Haluk (Springer Heidelberg, 2022)The purpose of this study was to investigate the efects of treadmill exercise training on obesity-induced behavioral changes in high-fat diet (HFD)-induced male rats. In this study, 40 male Sprague–Dawley rats were divided ...
