Yazar "Küçükislamoğlu, Mustafa" için listeleme
-
Evaluation of new chalcone derivatives as polyphenol oxidase inhibitors
Sönmez, Fatih; Sevmezler, Sedat; Atahan, Alparslan; Ceylan, Mustafa; Demir, Dudu; Gençer, Nahit; Arslan, Oktay; Küçükislamoğlu, Mustafa (Pergamon-Elsevier Science Ltd, 2011)A newly series of 4-(phenylurenyl) chalcone (4a-j) and 4'-(phenylurenyl/thiourenyl)chalcone (9a-l) derivatives were synthesized and their inhibitory effects on the diphenolase activity of banana tyrosinase were evaluated. ... -
In vitro inhibition effect and structure-activity relationships of some saccharin derivatives on erythrocyte carbonic anhydrase I and II
Sönmez, Fatih; Bilen, Çiğdem; Sümersan, Sinem; Gençer, Nahit; Işık, Semra; Arslan, Oktay; Küçükislamoğlu, Mustafa (Taylor & Francis Ltd, 2014)In this study, in vitro inhibitory effects of some saccharin derivatives on purified carbonic anhydrase I and II were investigated using CO2 as a substrate. The results showed that all compounds inhibited the hCA I and hCA ... -
In vitro inhibition effect of some chalcones on erythrocyte carbonic anhydrase i and II
Gençer, Nahit; Bilen, Çiğdem; Demir, Dudu; Atahan, Alparslan; Ceylan, Mustafa; Küçükislamoğlu, Mustafa (Informa Healthcare, 2013)In this study, 4'-(phenylurenyl/thiourenyl) chalcones (14-25) were prepared from 4'-(phenylurenyl/thiourenyl)acetophenones and benzaldehyde derivatives by Claisen-Schmidt condensation. In vitro inhibition effects of chalcone ... -
In vitro inhibition effects on erythrocyte carbonic anhydrase I and II and structure-activity relationships of cumarylthiazole derivatives
Kurt, Belma Zengin; Sönmez, Fatih; Gökçe, Başak; Ergün, Adem; Gencer, Nahit; Demir, Taki; Arslan, Oktay; Küçükislamoğlu, Mustafa (Maik Nauka, 2016)Coumarin and heterocyclic compounds incorporating urea have clinical applications as antiepileptics, diuretics, and antiglaucoma agents due to their carbonic anhydrase inhibitory properties. We investigated inhibition of ... -
New saccharin derivatives as tyrosinase inhibitors
Gençer, Nahit; Demir, Dudu; Sönmez, Fatih; Küçükislamoğlu, Mustafa (Pergamon-Elsevier Science Ltd, 2012)A newly series of 6-(phenylurenyl/thiourenyl) saccharin (6a-y) derivatives were synthesized and their inhibitory effects on the diphenolase activity of banana tyrosinase were evaluated. A 70-fold purification of the enzyme ... -
Synthesis and in vitro inhibition effect of new pyrido[2,3-d] pyrimidine derivatives on erythrocyte carbonic anhydrase i and ii
Kuday, Hilal; Sönmez, Fatih; Bilen, Çiğdem; Yavuz, Emre; Gençer, Nahit; Küçükislamoğlu, Mustafa (Hindawi Publishing Corporation, 2014)In vitro inhibition effects of indolylchalcones and new pyrido[2,3-d] pyrimidine derivatives on purified human carbonic anhydrase I and II (hCA I and II) were investigated by using CO2 as a substrate. The results showed ... -
Synthesis, antioxidant and carbonic anhydrase I and II inhibitory activities of novel sulphonamide-substituted coumarylthiazole derivatives
Kurt, Belma Zengin; Sönmez, Fatih; Bilen, Çiğdem; Ergün, Adem; Gençer, Nahit; Arslan, Oktay; Küçükislamoğlu, Mustafa (Taylor & Francis Ltd, 2016)New secondary benzenesulphonamide-substituted coumarylthiazole derivatives were synthesized and their inhibitory effects on purified carbonic anhydrase I and II were evaluated using CO2 as a substrate. The result showed ... -
Synthesis, structure-activity relationships and biological activity of new isatin derivatives as tyrosinase ınhibitors
Gençer, Nahit; Sönmez, Fatih; Demir, Dudu; Arslan, Oktay; Küçükislamoğlu, Mustafa (Bentham Science Publ Ltd, 2014)A newly series of isatin derivatives (6a-t) containing alkyl/aryl urea groups were synthesized and their inhibitory effects on the diphenolase activity of banana tyrosinase were evaluated. Tyrosinase was purified from ...
