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Amphenicol and macrolide derived antibiotics inhibit paraoxonase enzyme activity in human serum and human hepatoma cells (HepG2) in vitro
Sinan, Selma; Köçkar,Feray; Gençer, Nahit; Yıldırım, Hatice Kalkan; Arslan, Oktay (Maik Nauka/Interperiodıca/Springer, 2006)Human serum paraoxonase (hPON 1) was separately purified by ammonium sulfate precipitation and hydrophobic interaction chromatography The in vitro effects of commonly used antibiotics, namely clarithromycin and chloramphenicol, ... -
Are reference genes, GAPDH, beta-Actin and H-beta-2-microgloblin affected under normoxic and hypoxic conditions in Hep3B cells?
Türkoğlu, Sümeyye Aydoğan; Sunay, B.; Yıldırım, Hatice Kalkan; Köçkar,Feray (Wiley-Blackwell, 2011)Abstract:The appropriate choice of an internal standard is criti-cal for quantitative RNA analyses. As housekeeping genes, glyc-eraldehyde-3-phosphate dehydrogenase (GAPDH),b-Actin andH-b-2-Microgloblin are commonly employed ... -
Cloning of human ADAMTS-2 Promoter: Strategies for cloning extremely GC rich promoters
Alper, Meltem; Köçkar,Feray (Wiley-Blackwell, 2011)ADAMTS (A Disintegrin and Metalloproteinase with Thrombo-spondin Motifs) are zinc dependent proteases have a part in impor-tant physiologic processes such as development, homeostasis andfertility. To date, 19 different ...