Yazar "Gümüş, Arzu" için listeleme
-
Cyclization of acyl thiosemicarbazides led to new Helicobacter pylori α-carbonic anhydrase inhibitors
Gümüş, Arzu; D'Agostino, Ilaria; Puca, Valentina; Crocetta, Valentina; Carradori, Simone; Cutarella, Luigi; Mori, Mattia; Carta, Fabrizio; Angeli, Andrea; Capasso, Clemente; Supuran, Claudiu T. (John Wiley and Sons Inc, 2024)The eradication of Helicobacter pylori, the etiologic agent of gastric ulcer and adenocarcinoma, is a big concern in clinics due to the increasing drug resistance phenomena and the limited number of efficacious treatment ... -
N,N'-Dialkil disübstitüe diaza crown eter bileşiklerinin sentezi ve karakterizasyonu
Gümüş, Arzu (Balıkesir Üniversitesi Fen Bilimleri Enstitüsü, 2004)Tez çalışmamızda; N,N'-Didodesil 1,14-diimino 3,4;12,13-dibenzo 5,8,11- trioksa pentadekan (AA1), N,N'-Didodesil 1,17-diimino 3,4;15,16-dibenzo 5,8,1 1,14-tetraoksa oktadekan (ABİ), N,N'-Didodesil 1,15-diamino 3,4;12,13- ... -
Privileged scaffolds in medicinal chemistry: Studies on pyrazolo[1,5-a]pyrimidines on sulfonamide containing Carbonic Anhydrase inhibitors
Gümüş, Arzu; Bozdağ, Murat; Angeli, Andrea; Peat, Thomas S.; Carta, Fabrizio; Supuran, Claudiu T.; Selleri, Silvia (Pergamon-Elsevier Science Ltd, 2021)We report for the first time a small series of compounds endowed in vitro with inhibitory properties for the human (h) expressed Carbonic Anhydrase (CAs, E.C. 4.2.1.1) enzymes of physiological interest (i.e. I, II, VA, IX ... -
A study of complexation-ability of neutral Schiff bases to some metal cations
Topal, Giray; Tümerdem, Recep; Başaran, İsmet; Gümüş, Arzu; Çakır, Ümit (Mdpi Ag, 2007)The constants of the extraction equilibrium and the distribution for dichloromethane as an organic solvent having low dielectric constant of metal cations with chiral Schiff bases, benzaldehydene-(S)- 2- amino- 3- ... -
Synthesis and extraction studies of some new anionic dye extractors
Uğraş, H. İbrahim; Gümüş, Arzu; Başaran, İsmet; Çakır, Ümit (Taylor & Francis Inc, 2008)A new series of dodecyl derivatives of non-cyclic and cyclic ethers, as the extractors have been synthesized by imination, reduction of imines and cyclization steps, and the structures were identified by FT-IR, (1)H-NMR, ... -
Synthesis, antielastase, antioxidant and radical scavenging activities of 4-(aza substituted) methylene substituted dihydroxy coumarines
Sökmen, Bahar Bilgin; Aydın, Gülşah; Gümüş, Arzu; Karadeniz, Şeref; Uğraş, Halil İbrahim; Yanardağ, Refiye; Çakır, Ümit (Informa Healthcare, 2013)A series of some 4-(aza substituted) methylene substituted dihydroxy coumarines were evaluated for their antioxidant and antielastase activities. Different in vitro methodologies such as total reducing power, 1,1-dipheny ... -
Synthesis, complexation, and biological activity studies of 4-aminomethyl-7,8-dihydroxy coumarines and their crown ether derivatives
Gümüş, Arzu; Karadeniz, Şeref; Uğraş, Halil İbrahim; Bulut, Mustafa; Çakır, Ümit; Gören, Ahmet Ceyhan (Wiley-Blackwell, 2010)The article focuses synthesis of novel 4-aminomethyl-7,8-dihydroxy coumarins and their crown ether derivatives. The purified novel coumarins and their crown ether derivatives were identified by (1)H NMR, (13)C NMR, mass ... -
Thiosemicarbazide-substituted coumarins as selective inhibitors of the tumor associated human carbonic anhydrases IX and XII
Gümüş, Arzu; Bozdağ, Murat; Akdemir, Atilla; Angeli, Andrea; Selleri, Silvia; Carta, Fabrizio; Supuran, Claudiu T. (MDPI, 2022)A novel series of thiosemicarbazide-substituted coumarins was synthesized and the inhibitory effects against four physiologically relevant carbonic anhydrase isoforms I, II, IX and XII showed selective activities on the ...
