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Biochemical, pathological and ultrastructural investigation of whether lamotrigine has neuroprotective efficacy against spinal cord ischemia reperfusion injury
Kahveci, Fatih Ozan; Kahveci, Ramazan; Gökçe, Emre Cemal; Gökçe, Aysun; Kısa, Üçler; Sargon, Mustafa Fevzi; Fesli, Ramazan; Sarı, Muhammed Fatih; Gürer, Bora (Elsevier Sci Ltd, 2021)Introduction: Lamotrigine, an anticonvulsant drug with inhibition properties of multi-ion channels, has been shown to be able to attenuates secondary neuronal damage by influencing different pathways. The aim of this study ... -
Borax partially prevents neurologic disability and oxidative stress in experimental spinal cord ischemia/reperfusion injury
Koç, Emine Rabia; Gökçe, Emre Cemal; Sönmez, Mehmet Akif; Namuslu, Mehmet; Gökçe, Aysun; Bodur, Abdurrahman Said (Elsevier Science Bv, 2015)Objectives: The aim of this study is to investigate the potential effects of borax on ischemia/reperfusion injury of the rat spinal cord. Methods: Twenty-one Wistar albino rats were divided into 3 groups: sham (no ... -
Effects of ganoderma lucidum polysaccharides on different pathways involved in the development of spinal cord ischemia reperfusion injury: Biochemical, histopathologic, and ultrastructural analysis in a rat model
Kahveci, Ramazan; Kahveci, Fatih Ozan; Gökçe, Emre Cemal; Gökçe, Aysun; Kısa, Üçler; Sargon, Mustafa Fevzi; Fesli, Ramazan; Gürer, Bora (Elsevier Sci Inc, 2021)OBJECTIVE: Inflammation and oxidative stress are 2 important factors in the emergence of paraplegia associated with spinal cord ischemia-reperfusion injury (SCIRI) after thoracoabdominal aortic surgery. Here it is aimed ... -
An experimental comparison of the effects of propolis, curcumin, and methylprednisolone on crush ınjuries of the sciatic nerve
Yüce, Serdar; Gökçe, Emre Cemal; Işıkdemir, Ahmet; Koç, Emine Rabia; Cemil, Duran Berker; Gökçe, Aysun; Sargon, Mustafa (Lippincott Williams & Wilkins, 2015)Background: Propolis and curcumin have antioxidant, anti-inflammatory, immunomodulatory, and neuroprotective features. The goal of this study was to determine the effects of propolis and curcumin on nerve healing in rat ...