Yazar "Ergun, Adem" için listeleme
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Development of carbazole-bearing pyridopyrimidine-substituted urea/thiourea as polyphenol oxidase inhibitors: synthesis, biochemistry, and theoretical studies
Nixha, Arleta Rifati; Ergun, Adem; Gencer, Nahit; Arslan, Oktay; Arslan, Mustafa (Taylor and Francis Ltd, 2019)Polyphenol oxidase (Tyrosinase, PPO) has received considerable attention, since it is the key enzyme in melanin biosynthesis. In this study, we investigated prepared novel carbazole-containing pyridopyrimidine-substituted ... -
Evaluation of carbonic anhydrase and paraoxonase inhibition activities and molecular docking studies of highly water-soluble sulfonated phthalocyanines
Güzel, Emre; Sönmez, Fatih; Erkan, Sultan; Çıkrıkçı, Kübra; Ergun, Adem; Gencer, Nahit; Arslan, Oktay; Koçak, Makbule Burkut (Scientific Technical Research Council Turkey-Tubitak, 2020)The investigation of carbonic anhydrase and paraoxonase enzyme inhibition properties of water-soluble zinc and gallium phthalocyanine complexes (1 and 2) are reported for the first time. The binding of p-sulfonylphenoxy ... -
Microwave-assisted synthesis of 1-substituted-1H-benzimidazolium salts: Non-competitive inhibition of human carbonic anhydrase I and II
Karlık, Özgül; Gencer, Nahit; Karataş, Mert O.; Ergun, Adem; Çıkrıkcı, Kübra; Arslan, Oktay; Alıcı, Bülent; Cıkla, Işın Kılıç; Özdemir, Namık (Wiley-V C H Verlag GMBH, 2019)A series of 1-substituted-1H-benzimidazolium p-toluenesulfonate salts were synthesized in good yields by the reaction of 1-substituted benzimidazole derivatives and p-toluenesulfonic acid under microwave irradiation. Two ... -
Synthesis of new series of thiazol-(2(3H)-ylideneamino)benzenesulfonamide derivatives as carbonic anhydrase inhibitors
Berber, Nurcan; Arslan, Mustafa; Vural, Fırat; Ergun, Adem; Gencer, Nahit; Arslan, Oktay (Wiley, 2020)Human carbonic anhydrase I and II isoenzymes (hCA I and II) are important metabolic enzymes. In this study, a new series of thiazol-(2(3H)-ylideneamino)benzenesulfonamide derivatives were synthesized and also some inhibition ... -
Synthesis, in vitro inhibition effect of novel phthalocyanine complexes as carbonic anhydrase and paraoxonase enzyme inhibitors
Güzel, Emre; Arslan, Barış Seçkin; Çıkrıkcı, Kübra; Ergun, Adem; Gencer, Nahit; Arslan, Oktay; Şişman, İlkay; Nebioğlu, Mehmet (World Sci Publ Co Inc, 2020)The preparation and assessment of carbonic anhydrase and paraoxonase enzyme inhibition properties of 3-(2-(5-amino-4-(4-bromophenyl)-3-methyl-1H-pyrazol-1-yl)ethoxy)phthalonitrile (2) and its nitrogen-containing non-peripheral ...
