Yazar "Elmas, Levent" için listeleme
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Erianin, a promising agent in the treatment of glioblastoma multiforme triggers apoptosis in U373 and A172 glioblastoma cells
Koçoğlu, Sema Serter; Seçme, Mücahit; Elmas, Levent (Inst Bioloska Istrazivanja Sinisa Stankovic, 2022)Glioblastoma is an aggressive, common and deadly primary intracranial brain tumor in adults. The antitumor activity of erianin, a dibenzyl compound found in Dendrobium chrysotoxum Lindl. extract, has not been previously ... -
Erianinin HT29 kolorektal kanser hücrelerinin proliferasyonu ve koloni oluşumu üzerine etkilerinin araştırılması
Koçoğlu, Sema Serter; Elmas, Levent; Seçme, Mücahit (Seyhan Miğal, 2021)Kolorektal kanser, dünyada kanser ilişkili ölümlerin en yaygın dördüncü sebebidir. Erianin antioksidan ve anti-tümör etkilere sahip Dendrobium ekstraktından elde edilen yeni bir dibenzil bileşiğidir. Bu çalışmada, erianinin ... -
Granzyme B levels and granzyme B polymorphisms in peripheral blood of patients with endometriosis: a preliminary study
Taşkın, Mine İslimye; Güney, Gürhan; Adalı, Ertan; Hişmioğulları, Adnan Adil; Dodurga, Yavuz; Elmas, Levent (Taylor and Francis Inc, 2020)The chronic course of endometriosis suggests that the immune system may play a role in its aetiology. There may be resistance to cell lysis, as well as an immune defect underlying endometriosis. Granzyme B is a serine ... -
Monensin, an antibiotic isolated from streptomyces cinnamonensis, regulates human neuroblastoma cell proliferation via the PI3K/AKT signaling pathway and acts synergistically with rapamycin
Koçoğlu, Sema Serter; Seçme, Mücahit; Oy, Ceren; Korkusuz, Gözde; Elmas, Levent (MDPI, 2023)Neuroblastoma is the most common extracranial childhood tumor and accounts for approximately 15% of pediatric cancer-related deaths. Further studies are needed to identify potential therapeutic targets for neuroblastoma. ... -
The role of ERK-1 and ERK-2 gene polymorphisms in PCOS pathogenesis
Güney, Gürhan; Taşkın, Mine İslimye; Şener, Nazlı; Tolu, Ezgi; Dodurga, Yavuz; Elmas, Levent; Çetin, Orkun; Sarıgül, Cengiz (BMC, 2022)Background: Ovulation is regulated by extracellular signal-regulated kinase-1 (ERK-1) and ERK-2 signaling mechanisms, and ERK-1/2 kinases modulates the function of most of the LH-regulated genes. Defective ERK kinase ...
