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Sulfonamide inhibition study of the beta-class carbonic anhydrase from the caries producing pathogen streptococcus mutans

Dedeoğlu, Nurcan; Deluca, Viviana; Işık, Semra; Yıldırım, Hatice; Köçkar, Feray; Capasso, Clemente; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2015)

Streptococcus mutans, the oral pathogenic bacterium provoking dental caries formation, encodes for a beta-class carbonic anhydrase (CA, EC 4.2.1.1), SmuCA. This enzyme was cloned, characterized and investigated for its ...