Yazar "De Simone, Giovanni" için listeleme
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Drug design studies of the novel antitumor targets carbonic anhydrase IX and XII
Güler, Özen Özensoy; De Simone, Giovanni; Supuran, Claudiu T. (Bentham Science Publ Ltd, 2010)The carbonic anhydrase (CA, EC 4.2.1.1) isozymes IX and XII are predominantly found in tumor cells and show a restricted expression in normal tissues. By efficiently hydrating carbon dioxide to protons and bicarbonate, ...