Yazar "Capasso, Clemente" için listeleme
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Anion inhibition studies of the α-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae
Vullo, Daniela; Işık, Semra; Del Prete, Sonia; De Luca, Viviana; Carginale, Vincenzo; Scozzafava, Andrea; Supuran, Claudiu; Capasso, Clemente (Pergamon - Elsevier Ltd, 2013)An alpha-carbonic anhydrase (CA, EC 4.2.1.1) has been recently cloned and characterized in the human pathogenic bacterium Vibrio cholerae, denominated VchCA (Del Prete et al. J. Med. Chem. 2012, 55, 10742). This enzyme ... -
Cloning, characterization and anion inhibition study of a beta-class carbonic anhydrase from the caries producing pathogen streptococcus mutans
Dedeoğlu, Nurcan; De Luca, Viviana; Işık, Semra; Yıldırım, Hatice; Köçkar, Feray; Capasso, Clemente; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2015)The oral pathogenic bacterium involved in human dental caries formation Streptococcus mutans, encodes for two carbonic anhydrase (CA, EC 4.2.1.1) one belonging to the alpha- and the other one to the beta-class. This last ... -
Cyclization of acyl thiosemicarbazides led to new Helicobacter pylori α-carbonic anhydrase inhibitors
Gümüş, Arzu; D'Agostino, Ilaria; Puca, Valentina; Crocetta, Valentina; Carradori, Simone; Cutarella, Luigi; Mori, Mattia; Carta, Fabrizio; Angeli, Andrea; Capasso, Clemente; Supuran, Claudiu T. (John Wiley and Sons Inc, 2024)The eradication of Helicobacter pylori, the etiologic agent of gastric ulcer and adenocarcinoma, is a big concern in clinics due to the increasing drug resistance phenomena and the limited number of efficacious treatment ... -
DNA cloning, characterization, and inhibition studies of an alpha-carbonic anhydrase from the pathogenic bacterium vibrio cholerae
Del Prete, Sonia; Işık, Semra; Vullo, Daniela; De Luca, Viviana; Carginale, Vincenzo; Scozzafava, Andrea; Supuran, Claudiu T.; Capasso, Clemente (Amer Chemical Soc, 2012)We have cloned, purified, and characterized an alpha-carbonic anhydrase (CA, EC 4.2.1.1) from the human pathogenic bacterium Vibrio cholerae, VchCA. The new enzyme has significant catalytic activity, and an inhibition study ... -
Sulfonamide inhibition study of the beta-class carbonic anhydrase from the caries producing pathogen streptococcus mutans
Dedeoğlu, Nurcan; Deluca, Viviana; Işık, Semra; Yıldırım, Hatice; Köçkar, Feray; Capasso, Clemente; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2015)Streptococcus mutans, the oral pathogenic bacterium provoking dental caries formation, encodes for a beta-class carbonic anhydrase (CA, EC 4.2.1.1), SmuCA. This enzyme was cloned, characterized and investigated for its ...
