Yazar "Bolat, Gül Ünsel" için listeleme
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Association of ABCA13 gene variants with autism spectrum disorder and other neuropsychiatric disorders
Çelebi, Hamide Betül Gerik; Bolat, Gül Ünsel; Bolat, Hilmi (Karger, 2023)Introduction: Autism spectrum disorder (ASD) is a neuropsychiatric disorder characterized by impaired social skills and limited or repetitive behaviors. In this study, we investigated the role of the ABCA13 gene in the ... -
Autosomal recessive primary microcephaly (MCPH) and novel pathogenic variants in ASPM and WDR62 genes
Bolat, Hilmi; Sağer, Safiye Güneş; Türkyılmaz, Ayberk; Çebi, Alper Han; Akın, Yasemin; Onay, Hüseyin; Özkınay, Ferda; Bolat, Gül Ünsel (Karger, 2022)Introduction: Autosomal recessive primary microcephaly (MCPH) is a disorder characterized by congenital microcephaly and intellectual disability without extra-central nervous system malformation. MCPH is a disease with ... -
Case report: diagnosis and treatment of attention deficit hyperactivity disorder and autism spectrum disorder in patients diagnosed with oculocutaneous albinism
Bolat, Gül Ünsel (Routledge Journals, 2020)Oculocutaneous albinism (OCA) is a group of autosomal recessive disorders characterized by impairment in the melanin synthesis. We report two siblings with OCA who presented with symptoms of autism spectrum disorder and ... -
Clinical and genetic characteristics of patients with unexplained intellectual disability/developmental delay without epilepsy
Çelebi, Hamide Betül Gerik; Aydın, Hilal; Bolat, Hilmi; Bolat, Gül Ünsel (Karger, 2023)Introduction: Global developmental delay (DD), intellectual disability (ID), and autism spectrum disorder (ASD) are mainly evaluated under the neurodevelopmental disorder framework. In this study, we aimed to determine the ... -
Cohen syndrome: Can early-onset recurrent infections and hypotonia provide early diagnosis and intervention for intellectual disability?
Bolat, Gül Ünsel; Çelebi, Ezgi Keskin; Bolat, Hilmi (John Wiley and Sons Inc, 2024)Introduction: Cohen syndrome is a rare disease associated with neurodevelopmental disorders, especially intellectual disability (ID), neutropenia and recurrent infections are consistently reported in cases. Neutropenia is ... -
Diffusion tensor imaging findings in children with sluggish cognitive tempo comorbid Attention Deficit Hyperactivity Disorder
Bolat, Gül Ünsel; Baytunca, Muharrem Burak; Kardaş, Burcu; İpçi, Melis; İzmir, Sevim Berrin İnci; Özyurt, Onur; Çallı, Mehmet Cem; Ercan, Eyüp Sabri (Taylor and Francis Ltd, 2020)Objective:The construct of Sluggish Cognitive Tempo (SCT) is characterized by daydreaming, mental confusion, staring blankly and hypoactivity. Our main goal was to explore neuropsychological differences in Attention Deficit ... -
Dikkat eksikliği hiperaktivite bozukluğu ve madde kullanım bozukluğu eş tanısı olan ergenlerin taranması, tanısı ve tedavisi için uluslararası fikir birliği beyanı
Özgen, Mihriban Heval; Bolat, Gül Ünsel; Spijkerman, Renske; Brink, Wim van den; Hendriks, Vincent; Ercan, Eyüp Sabri; Emiroğlu, Neslihan İnal (Erkan Mor, 2021)Çocukluk çağı dikkat eksikliği hiperaktivite bozukluğu (DEHB) ergenlik ve (erken) yetişkinlikte madde kötüye kullanımı ve madde kullanım bozukluğu (MKB) için bir risk faktörüdür. Ayrıca, DEHB ve MKB tedavi arayan ergenlerde ... -
Distinct autism spectrum disorder phenotype and hand-flapping stereotypes: Two siblings with novel homozygous mutation in TRAPPC9 gene and literature review
Bolat, Hilmi; Bolat, Gül Ünsel; Derin, Hatice; Şen, Aşkın; Ceylaner, Serdar (Karger, 2022)Objective: Pathogenic mutations of the TRAPPC9 gene are the rare genetic causes of autosomal recessive intellectual disability (ID). There are several features that are not fully penetrant such as microcephaly, dysmorphic ... -
Down sendromu tanılı olgularda aile ve çocuğa ait sosyodemografik özelliklerin değerlendirilmesi
Bolat, Hilmi; Bolat, Gül Ünsel (Balıkesir Üniversitesi, 2022)Amaç: Çalışmanın amacı Down Sendromu (DS) tanılı çocuklara ve ailelerine ait sosyo-demografik özelliklerinin belirlenmesi, gebelik döneminde tarama ve tanı olanaklarına ulaşım oranlarının ve doğum sonrası gerekli sağlık ... -
DRD4 genotyping may differentiate symptoms of attention-deficit/hyperactivity disorder and sluggish cognitive tempo
Bolat, Hilmi; Ercan, Eyüp S.; Bolat, Gül Ünsel; Tahıllıoğlu, Akın; Yazıcı, Kemal U.; Bacanlı, Ali; Parıltay, Erhan; Jafari, Duygu Aygüneş (Assoc Brasileira Psiquiatria, 2020)Objective: Studies to reduce the heterogeneity of attention-deficit/hyperactivity disorder (ADHD) have increased interest in the concept of sluggish cognitive tempo (SCT). The aim of this study was to investigate if the ... -
Effect of impairment on the prevalence and comorbidities of attention deficit hyperactivity disorder in a national survey: Nation-wide prevalence and comorbidities of ADHD
Ercan, Eyüp Sabri; Bolat, Gül Ünsel; Tufan, Ali Evren; Demirkaya, Sevcan Karakoç; Bilac, Öznur; Çelik, Goncagül; Kılıç, Birim Günay; Ardıç, Ülkü Akyol (Sage Publications Inc, 2021)Objective: This study aimed to determine the prevalence and comorbidities of attention-deficit hyperactivity disorder (ADHD) by evaluating a large-scale nation-wide sample of children. Method: The inclusion criterion was ... -
Effects of covid-19 pandemic on the psychological states of youth and adult elite male athletes
Lima, Yavuz; Şenışık, Seçkin; Denerel, Nevzat; Hurşitoğlu, Onur; Balcı, Görkem A.; Bolat, Gül Ünsel; Ergün, Metin (Türkiye Spor Hekimleri Derneği, 2022)Objectve: Although the psychological states of athletes were negatively affected during the COVID-19 pandemic, there is a lack of studies examining the psychological impact on athletes according to age, sports discipline, ... -
Effects of COVID-19 pandemic on the psychological states of youth and adult elite male athletes
Balcı, Görkem A.; Şenışık, Seçkin; Lima, Yavuz; Denerel, Nevzad; Hurşitoğlu, Onur; Bolat, Gül Ünsel; Ergün, Metin (2022)Objective: Although the psychological states of athletes were negatively affected during the COVID-19 pandemic, there is a lack of studies examining the psychological impact on athletes according to age, sports discipline, ... -
Effects of the dopamine transporter gene on neuroimaging findings in different attention deficit hyperactivity disorder presentations
Bacanlı, Ali; Bolat, Gül Ünsel; Süren, Serkan; Yazıcı, Kemal Utku; Calli, Cem; Jafari, Duygu Aygüneş; Kosova, Buket; Rohde, Luis Augusto (Springer, 2021)Attention-Deficit/Hyperactivity Disorder (ADHD) is a phenotipically and neurobiologically heterogeneous disorder. Deficiencies at different levels in response inhibition, differences in dopamine transporter genotype (DAT1) ... -
Gelişim geriliği/entellektüel yetersizliği olan çocuklarda etiyolojiye yönelik genetik testlerin planlama ve değerlendirmesinde güncel durum: Tek merkez deneyimi
Bolat, Hilmi; Çelebi, Hamide Betül Gerik; Bolat, Gül Ünsel; Geniş, Esra Çolak; Demircan, Özge; Çam, Fethi Sırrı (Manisa Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü, 2022)Giriş ve Amaç: Gelişim geriliği (GG) ve entelektüel yetersizlik (EY) fenotipik ve genetik olarak heterojen bir grup hastalıktır. GG/EY olguların etiyolojisinde altta yatan önemli bir kısmını genetik nedenler oluşturmaktadır. ... -
Gelişim Geriliği|Entellektüel Yetersizliği Olan Çocuklarda Etiyolojiye Yönelik Genetik Testlerin Planlama ve DeğerlendirmesindeGüncel Durum: Tek Merkez Deneyimi
Geniş, Esra Çolak; Bolat, Gül Ünsel; Bolat, Hilmi; Demircan, Özge; Çelebi, Hamide Betül Gerik; Çam, Fethi Sırrı (2022)Giriş ve Amaç: Gelişim geriliği (GG) ve entelektüel yetersizlik (EY) fenotipik ve genetik olarak heterojen bir grup hastalıktır. GG/EY olguların etiyolojisinde altta yatan önemli bir kısmını genetik nedenler oluşturmaktadır. ... -
Increased cerebral blood flow in the right anterior cingulate cortex and fronto-orbital cortex during go/no-go task in children with ADHD
Baytunca, Muharrem Burak; de Frederick, Blaise; Bolat, Gül Ünsel; Kardaş, Burcu; İnci, Sevim Berrin; İpçi, Melis; Çallı, Cem; Özyurt, Onur (Taylor & Francis Ltd, 2021)Objective Arterial spin labeling (ASL) is a relatively new imaging modality in the field of the cognitive neuroscience. In the present study, we aimed to compare the dynamic regional cerebral blood flow alterations of ... -
Investigation of patients with childhood epilepsy in single center: Comprehensive genetic testing experience
Çelebi, Hamide Betul Gerik; Çetin, İpek Dokurel; Bolat, Hilmi; Bolat, Gül Ünsel (Wiley, 2024)Introduction: Epilepsy is a common multifactorial neurological disease usually diagnosed during childhood. In this study, we present the contribution of consecutive genetic testing to the genetic diagnostic yield of childhood ... -
Investigation of possible associations of the BDNF, SNAP-25 and SYN III genes with the neurocognitive measures: BDNF and SNAP-25 genes might be involved in attention domain, SYN III gene in executive function
Bolat, Hilmi; Bolat, Gül Ünsel; Özgül, Semiha; Parıltay, Erhan; Tahıllıoğlu, Akın; Rohde, Luis Augusto; Akın, Haluk (Taylor & Francis Ltd, 2022)Objectives Attention-deficit/hyperactivity disorder (ADHD) is a heterogeneous disorder and Sluggish Cognitive Tempo (SCT) might be a second inattention disorder that might be even affected by different attention pathways. ... -
Natural disasters as a maternal prenatal stressor and children's neurodevelopment: A systematic review
The intrauterine period is a time of high sensitivity in the development of the embryo and the fetus. Therefore, low levels of maternal stress are closely associated with healthy brain development in the neonatal and ...
