Yazar "Aydın, Meltem" için listeleme
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Carbonic anhydrase activators: Activation of the β-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids
Işık, Semra; Köçkar, Feray; Aydın, Meltem; Arslan, Oktay; Güler, Özen Özensoy; Innocenti, Alessio; Scozzafava, Andrea; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2009)The protein encoded by the Nce103 gene of Saccharomyces cerevisiae, a beta-carbonic anhydrase (CA, EC 4.2.1.1) designated as scCA, was investigated for its activation with amines and amino acids. scCA was poorly activated ... -
Carbonic anhydrase inhibitors: Inhibition of the β-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates
Işık, Semra; Köçkar, Feray; Aydın, Meltem; Arslan, Oktay; Güler, Özen Özensoy; Innocenti, Alessio; Scozzafava, Andrea; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2009)The protein encoded by the Nce103 gene of Saccharomyces cerevisiae, a beta-carbonic anhydrase ( CA, EC 4.2.1.1) designated as scCA, has been cloned, purified, characterized kinetically and investigated for its inhibition ... -
Cloning and expression of human CAI in E-coli
Yıldırım, Hatice; Köçkar, Feray; Aydın, Meltem; Arslan, Oktay (Blackwell Publishing,, 2006)yok -
Cloning and expression of P-Brutia GST-zeta in E-coli
Aydın, Meltem; Köçkar, Feray; İşcan, Mehmet (Blackwell Publishing, 2007)GlutathioneS-Transferases (GSTs, EC.2.5.1.18) are complex andwidespread enzyme superfamily that detoxify endobiotics and xen-obiotics, and forming generally water soluble and less toxic gluta-thione(GSH)S-conjugate. Since ... -
Comparison of hydratase, esterase activities and inhibition manner of mutant Asn67/Ile and Leu204/Ser of human CAII
Türkoğlu, Sumeyye Aydoğan; Köçkar, Feray; Aydın, Meltem; Sinan, Selma; Arslan, Oktay (Blackwell Publishing, 2008)Carbonic anhydrases (CAs; also known as carbonate dehydratases EC 4.2.1.1) are a family of enzymes which catalyze the reversible reaction from H2O and CO2 to HCO3 - ions. Carbonic anhydrases are ubiquitous metalloenzymes ... -
İnsan karbonik anhidrazı (HCA I) geninin klonlanması, E.coli'de ekspresyonu ve Phe91Asn yönlendirilmiş mutageneziyle elde edilen mutant enzimin inhibitörlere karşı ilgisinin araştırılması
Aydın, Meltem (Balıkesir Üniversitesi Fen Bilimleri Enstitüsü, 2007)İnsan Karbonik Anhidraz (HCA I) (Karbonat hidroliyaz E.C. 4.2.1.1) 8. kromozomun uzun kolunda lokalize olan 30kDa büyüklüğünde bir proteindir. Eritrositlerde, kolon epitelinde, göz lensi ve korneal epitelyumda bulunur. ... -
Phylogenetic and bioinformatic analysis of glutathione s-transferase tau from pinus brutia
Öztetik, Elif; Aydın, Meltem; Köçkar, Feray (Wiley-Blackwell Publishing, 2009)Glutathione S-Transferases (GSTs, EC.2.5.1.18) are widespread and complex enzyme superfamily that play important roles in detoxification and stress tolerance in plants. Plant GSTs are divided into four classes (Phi, ... -
Saccharomyces cerevisiae beta-carbonic anhydrase: ınhibition and activation studies
Işık, Semra; Güler, Özen Özensoy; Köçkar, Feray; Aydın, Meltem; Arslan, Oktay; Supuran, Claudiu T. (Bentham Science Publ Ltd, 2010)The beta-carbonic anhydrase from Saccharomyces cerevisiae (CA, EC 4.2.1.1), scCA, which is encoded by the Nce103 gene, is an effective catalyst for CO2 hydration to bicarbonate and protons, with a k(cat) of 9.4 x 10(5) ... -
Sequence analysis of Tau class glutathione S-transferase from Pinus brutia (Pinaceae)
Öztetik, Elif; Aydın, Meltem; Köçkar, Feray (Wiley-Blackwell, 2008)Ubiquitously distributed multifunctional superfamily of Glutathione Stransferases (GST, EC.2.5.1.18) generally constitute a dimeric enzymes and catalyze the conjugation of the thiol group of the glutathione (GSH) to ... -
Update on treatment options for spinal brucellosis
Ulu-Kılıç, Ayşegül; Karakaş, Ahmet; Erdem, Hakan; Türker, Türker; İnal, Ayşe S.; Ak, Öznur; Turan, Hale; Aydın, Meltem (Wiley-Blackwell, 2014)We evaluated the efficacy and tolerability of antibiotic regimens and optimal duration of therapy in complicated and uncomplicated forms of spinal brucellosis. This is a multicentre, retrospective and comparative study ...
