Yazar "Angeli, Andrea" için listeleme
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Cyclization of acyl thiosemicarbazides led to new Helicobacter pylori α-carbonic anhydrase inhibitors
Gümüş, Arzu; D'Agostino, Ilaria; Puca, Valentina; Crocetta, Valentina; Carradori, Simone; Cutarella, Luigi; Mori, Mattia; Carta, Fabrizio; Angeli, Andrea; Capasso, Clemente; Supuran, Claudiu T. (John Wiley and Sons Inc, 2024)The eradication of Helicobacter pylori, the etiologic agent of gastric ulcer and adenocarcinoma, is a big concern in clinics due to the increasing drug resistance phenomena and the limited number of efficacious treatment ... -
Privileged scaffolds in medicinal chemistry: Studies on pyrazolo[1,5-a]pyrimidines on sulfonamide containing Carbonic Anhydrase inhibitors
Gümüş, Arzu; Bozdağ, Murat; Angeli, Andrea; Peat, Thomas S.; Carta, Fabrizio; Supuran, Claudiu T.; Selleri, Silvia (Pergamon-Elsevier Science Ltd, 2021)We report for the first time a small series of compounds endowed in vitro with inhibitory properties for the human (h) expressed Carbonic Anhydrase (CAs, E.C. 4.2.1.1) enzymes of physiological interest (i.e. I, II, VA, IX ... -
Thiosemicarbazide-substituted coumarins as selective inhibitors of the tumor associated human carbonic anhydrases IX and XII
Gümüş, Arzu; Bozdağ, Murat; Akdemir, Atilla; Angeli, Andrea; Selleri, Silvia; Carta, Fabrizio; Supuran, Claudiu T. (MDPI, 2022)A novel series of thiosemicarbazide-substituted coumarins was synthesized and the inhibitory effects against four physiologically relevant carbonic anhydrase isoforms I, II, IX and XII showed selective activities on the ...
