Yazar "Aksöz, Elif" için listeleme
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Age-related differences in the effect of vitamin D onscopolamine-induced learning and memory impairment
Karabulut, Medine; Baykan, Özgür; Aksöz, Elif (İnönü Üniversitesi Tıp Fakültesi, 2021)Aim: Alzheimer's disease is the most common type of dementia. The number of patients with Alzheimer's is expected to reach 115million in 2050. Due to the low effectiveness and frequent adverse effects of current treatment ... -
Changes in paraoxonase, β-glucosidase, and carbonic anhydrase enzymes related to age and scopolamine-induced memory impairment in rats
Yıldırım, Hatice; Aksöz, Elif; Daşkan, Burcu Efe; Şen, Fazilet; Çelebi, Murat (Multidisciplinary Digital Publishing Institute (MDPI), 2024)This study aimed to investigate the changes in Paraoxonase (PON), Carbonic Anhydrase (CA), and β-glucosidase levels of different aged rats and scopolamine-induced memory impairment rats. This study used young, adult, and ... -
Chronic etanercept treatment exerts antidepressant-like effect in cafeteria diet-fed rats
Utkan, Tijen; Demirtaş, Tuğçe; Aksöz, Elif; Arkan, Sertan (Elsevier Science BV, 2015)Purpose of the study: An increasing number of studies have revealed that obesity is associated with depression. Recent studies also have reported that obesity is not only as a metabolic disorder but also as an inflammatory ... -
Comparative plasma and milk dispositions,faecal excretion and efficacy of per os ivermectin and pour-on eprinomectin in horses
Gökbulut, Cengiz; Özüiçli, Mehmet; Akşit, Dilek; Aksöz, Elif; Korkut, Oǧuzhan; Yalçınkaya, M.; Çırak, Veli Yılgör (Wiley-Blackwell, 2016)The horse milk gains increasing interest as a food product for sensitive consumers, such as children with food allergies or elderly people. We investigated the plasma and milk disposition, faecal excretion and efficacy of ... -
Comparison of haematologic side effects of different pegylated interferon-α molecules combined with ribavirin
Aydın, Mehtap; Aksöz, Elif; Korkut, Oğuzhan; Akhan, Sıla Çetin (AVES Ibrahim Kara, 2014)Objective: Treatment of chronic hepatitis C virus (HCV) infection with pegylated interferon (PegIFN) and ribavirin causes haematological side effects such as anemia, neutropenia and trombocytopenia. This study aimed to ... -
Context Sensitive Links 16 of 395 Protective effects of p-coumaric acid against gentamicin-induced nephrotoxicity in rats
Hakyemez, İsmail Necati; Cevizci, Mehmet Nuri; Aksöz, Elif; Yılmaz, Kenan; Uysal, Saliha; Altun, Eren (Taylor & Francis, 2021)The most important side effect of gentamicin (GM) is nephrotoxicity. p-Coumaric acid (PCA) is a phenolic compound that scavenges free radicals, reduces fibrosis, and tissue damage. This study investigates the protective ... -
D vitamininin genç ve yaşlı sıçanlarda skopolaminle bozulmuş hafızaya etkisinin karşılaştırılması
Karabulut, Medine (Balıkesir Üniversitesi Sağlık Bilimleri Enstitüsü, 2020)Son yıllarda, D vitamininin sinir sistemi gelişimi ve fonksiyonunda ciddi bir aday ve çeşitli nörolojikpatolojilerde terapötik bir araç olabileceği tartışıklmaktadır. Deneysel ve klinik öncesi veriler D vitamini durumu ile ... -
Effect of etanercept, a tnf-alpha inhibitor, on depressive-like behavior in cafeteria diet-fed rats
Şahin, Tuğçe Demirtaş; Utkan, Tijen; Aksöz, Elif; Karson, Ayse (Elsevier Science BV, 2015)Background: Obesity has been shown to be associated with depression. Recent studies have reported that obesity is not only as a metabolic disorder but also as an inflammatory disease. In this study we explored the effect ... -
The effects of propolis extract on age-associated cognitive deficits in rats
Göçmez, Semil Selcen; Çelebi, G.; Demirtaş-Şahin, T.; Aksöz, Elif; Utkan, Tijen (Elsevier, 2019)Background: Propolis is widely used as alternative medicinal product due to their antimicrobial, antiinflammatory and antioxidant properties. Previous studies have shown that propolis has a neuroprotective effect and ... -
The effects of SSRI's plus sildenafil combination on vas deferens contraction
Aksöz, Elif; Bilge, Süleyman Sırrı; İlkaya, Fatih; Baş, B. Duygu; Kesim, Yüksel; Çelik, Süleyman (2009)Selective serotonin reuptake inhibitors (SSRIs) induced delayed ejaculation as an adverse effect. Cause of this they have been used to treat Premature Ejaculation. Recent studies have suggested that sildenafil, a selective ... -
Etanercept treatment prevents emotional memory deficits of cafeteria diet-fed rats
Şahin, Tuğçe Demirtaş; Utkan, Tijen; Aksöz, Elif; Karson, Ayşe (Elsevier Science BV, 2015)Background: Obesity has been shown to degrade cognitive functions, including memory. Recent evidence suggests that obesity also results in inflammation in the brain. In this study we investigated the effect of etanercept ... -
Evaluation of the effects of dexketoprofen trometamol on knee joint: An in vivo & in vitro study
Sağır, Özlem; Sunay, Fatma Bahar; Yıldırım, Hatice; Aksöz, Elif; Özaslan, Sabri; Köroğlu, Ahmet; Aydemir, Tuğşen; Ulusal, Ali Engin; Köçkar, Feray (Indian Council Medical RES, 2013)Background & objectives: Intra-articular (ia) injections of local anaesthetics and non-steroidal anti-inflammatory drugs (NSAID's) are simple and efficient to ensure post-operative analgesia but some of these have toxic ... -
Gentamisin kullanımına bağlı gelişen nefrotoksisitede b12 vitamininin etkilerinin araştırılması
Çelebi, Murat (Balıkesir Üniversitesi Sağlık Bilimleri Enstitüsü, 2024)Aminoglikozid grubu antibiyotiklerin kullanımına bağlı olarak %10-25 oranında nefrotoksisite gelişme ihtimali vardır. Aminoglikozid kullanımına bağlı nefrotoksisiteye karşı rutin olarak kullanılabilecek koruyucu ajan ... -
Gentamisine Bağlı Nefrotoksisiteyi Önleme Potansiyeli Olan Tedavilerin Gözden Geçirilmesi
Çelebi, Murat; Çelebi, Çağla; Aksöz, Elif (2023)Aminoglikozitler, düşük maliyetleri, yüksek etkililikleri ve diğer antibiyotiklere kıyasla nispeten düşük bakteri direncine sahip olmaları nedeniyle dünya çapında sıklıkla kullanılan antibiyotikler arasındadır. Yaygın ... -
Neuroprotective effects of Sideritis trojana essential oil in AlCl3-induced amnesic rats
Hayta, Şükrü; Bulmuş, Özgür; Aksöz, Elif; Uysal, Saliha; Akbaba, Emel (Har Krishan Bhalla and Sons, 2024)In this study, the effects of Sideritis trojana essential oil on memory, anxiety, and depression were investigated in rats subjected to AlCl3-induced dementia. The major constituents of S. trojana essential oil were analyzed ... -
Plasma disposition and faecal excretion of eprinomectin following topical and subcutaneous administration in non-lactating dairy cattle
Akşit, Dilek; Korkut, Oğuzhan; Aksöz, Elif; Gökbulut, Cengiz (Taylor & Francis Inc, 2016)AIMS: To investigate the plasma disposition and faecal excretion of eprinomectin (EPM) in non-lactating dairy cattle following topical and S/C administration.METHODS: Holstein dairy cows, 3.5-5 years-old, were selected ... -
The protective effect of metformin in scopolamine-induced learning and memory impairment in rats
Aksöz, Elif; Göçmez, Semil Selcen; Şahin, Tuğçe Demirtaş; Akşit, Dilek; Akşit, Hasan; Utkan, Tijen (Polish Acad Sciences Inst Pharmacology, 2019)Background: Alzheimer's disease (AD) is the most common neurodegenerative disease in the world. One of the most commonly prescribed oral antidiabetic drug, metformin, has been shown to have beneficial effects on restoring ... -
Protective effects of an extract of propolis in scopolamine-induced cognitive impairment in rats
Utkan, Tijen; Demirtaş Şahin, Tuğçe; Göçmez, Semil; Aksöz, Elif; Gacar, Nejat (Elsevier Science BV, 2015)Purpose: Propolis is a natural substance collected by honeybees from buds and exudates of certain trees which has antioxidant, antibacterial, antiviral and anti-inflammatory and neuroprotective effect in neurodegenerative ... -
Protective effects of metformin in scopolamine-induced cognitive impairment in rats
Aksöz, Elif; Göçmez, Semil Sevcen; Demirtaş, Tuğçe; Utkan, Tijen (Elsevier Science BV, 2015)Purpose:Epidemiological, clinical and experimental data supporta link between type 2 diabetes mellitus and Alzheimer’s disease(AD). AD is a progressive neurodegenerative disorder of the brainthat is characterized by ... -
Protective effects of quercetin on necrotizing enterocolitis in a neonatal rat model
Yazıcı, Selçuk; Özcan, Cansu Ünden; Hişmioğulları, Adnan Adil; Sunay, Fatma Bahar; Özcan, Teoman; Berksoy, Emel Ataş; Aksöz, Elif (Thieme Medical Publ Inc, 2018)Introduction Necrotizing enterocolitis (NEC) is one of the major health problems of newborn period. To date, a large amount of chemicals have been tested for NEC and some showed limited beneficial effects. The research for ...
