Yazar "Şahin, Hakan" için listeleme
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Comparative analysis of effects of conditioned mediums obtained from 2D or 3D cultured mesenchymal stem cells on kidney functions of diabetic rats: Early intervention could potentiate transdifferentiation of parietal epithelial cell into podocyte precursors
Özkan, Serbay; Işıldar, Başak; Şahin, Hakan; Saygı, Halil İbrahim; Konukoğlu, Dildar; Koyutürk, Meral (Elsevier, 2024)Aim: The secretome of mesenchymal stem cells (MSCs) could be a potential therapeutic intervention for diabetes and associated complications like nephropathy. This study aims to evaluate the effects of conditioned ... -
Effects of chronically exogenous oxytocin on ovary and uterus: A comparison of intraperitoneal and intranasal administration
Şentürk, Gözde Erkanlı; Sezer, Zehra; Şahin, Hakan; Işıldar, Başak; Abdulova, Aynur (Elsevier, 2023)Oxytocin (OT) has been studied as a therapeutic neuropeptide in various diseases, but its effect on the ovary and uterus is not fully known. This study investigates the effects of intranasal and intraperitoneal OT ... -
Effects of conditioned mediums collected from 2d or 3d cultured mscs on kidney functions of rats with autoimmune diabetes induced with streptozocin
Özkan, Serbay; Işıldar, Başak; Şahin, Hakan; Saygı, Halil İbrahim; Konukoğlu, Dildar; Koyutürk, Meral (Oxford Univ Press, 2023)Background and Aims: The main mechanism of therapeutic action of mesenchymal stem cells (MSCs) could be resulted from their secretome content rather than their direct differentiation into damaged cells [1, 2]. Preconditioning ... -
Elastik zemine oturan plaklar ve temel sistemlerinin çözümü
Şahin, Hakan (Balıkesir Üniversitesi Fen Bilimleri Enstitüsü, 1997)Elastik zemine oturan temel kirişi ve plakların hesabında yatak modülü yöntemi esas alınacağından, öncelikle yatak modülünün nasıl belirleneceği ele alınmış ve çeşitli zemin türleri için ortalama yatak modülü değerleri ... -
Preconditioning of human umbilical cord mesenchymal stem cells with deferoxamine potentiates the capacity of the secretome released from the cells and promotes immunomodulation and beta cell regeneration in a rat model of type 1 diabetes
Işıldar, Başak; Özkan, Serbay; Şahin, Hakan; Erçin, Merve; Oktayoğlu, Selda Gezginci; Koyutürk, Meral (Elsevier, 2024)This study aimed to examine the effects of the secretome released by human umbilical cord-mesenchymal stem cells (MSC) as a result of preconditioning with deferoxamine (DFX), a hypoxia mimetic agent, on type 1 diabetes ...