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Functionalized imidazolium and benzimidazolium salts as paraoxonase 1 inhibitors: Synthesis, characterization and molecular docking studies
Karataş, Mert Olgun; Uslu, Harun; Alıcı, Bülent; Gökçe, Başak; Gencer, Nahit; Arslan, Oktay; Arslan, N. Burcu; Özdemir, Namık (Pergamon-Elsevier Science Ltd, 2016)Paraoxonase (PON) is a key enzyme in metabolism of living organisms and decreased activity of PON1 was acknowledged as a risk for atherosclerosis and organophosphate toxicity. The present study describes the synthesis, ... -
Microwave-assisted synthesis of 1-substituted-1H-benzimidazolium salts: Non-competitive inhibition of human carbonic anhydrase I and II
Karlık, Özgül; Gencer, Nahit; Karataş, Mert O.; Ergun, Adem; Çıkrıkcı, Kübra; Arslan, Oktay; Alıcı, Bülent; Cıkla, Işın Kılıç; Özdemir, Namık (Wiley-V C H Verlag GMBH, 2019)A series of 1-substituted-1H-benzimidazolium p-toluenesulfonate salts were synthesized in good yields by the reaction of 1-substituted benzimidazole derivatives and p-toluenesulfonic acid under microwave irradiation. Two ...
